4-Methylchromene-2-thione

Base Information

Chemical Name:4-Methylchromene-2-thione
CAS No.:25624-32-2
Molecular Formula:C10H8OS
Molecular Weight:176.239
Hs Code.:
DSSTox Substance ID:DTXSID90368045
Wikidata:Q82154326
Mol file:25624-32-2.mol

Synonyms:4-methylchromene-2-thione;25624-32-2;4-methyl-2H-chromene-2-thione;2H-1-Benzopyran-2-thione, 4-methyl-;4-methylthiocoumarin;SCHEMBL8013758;DTXSID90368045;HMS1749I04;AKOS001025438;Z56755530;F0400-0018

Suppliers and Price of 4-Methylchromene-2-thione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-Methylchromene-2-thione

Chemical Property:

PSA：45.23000
LogP:3.47070
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:176.02958605
Heavy Atom Count:12
Complexity:232

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=S)OC2=CC=CC=C12

Technology Process of 4-Methylchromene-2-thione

There total 3 articles about 4-Methylchromene-2-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 607-71-6
4-methyl-2H-chromen-2-one

: 25624-32-2
4-methyl-2H-1-benzopyran-2-thione

Guidance literature:: With diphosphorus pentasulfide; In benzene; for 2h; Heating;

Reference yield:

: 118-93-4,104809-67-8
o-hydroxyacetophenone

: 25624-32-2
4-methyl-2H-1-benzopyran-2-thione

Guidance literature:: Multi-step reaction with 2 steps

2: tetraphosphorus decasulfide / benzene / 5 h / Reflux

With tetraphosphorus decasulfide; In benzene; 1: |Wittig Olefination;
DOI:10.1007/s11172-019-2641-x

Reference yield:

: 108-95-2,27073-41-2
phenol

: 25624-32-2
4-methyl-2H-1-benzopyran-2-thione

Guidance literature:: Multi-step reaction with 2 steps

1: aluminum (III) chloride / nitrobenzene / 3 h / 130 °C

2: tetraphosphorus decasulfide / benzene / 5 h / Reflux

With aluminum (III) chloride; tetraphosphorus decasulfide; In nitrobenzene; benzene;
DOI:10.1007/s11172-019-2613-1