[1,1'-Biphenyl]-2-amine, 2',4',6'-trimethyl-

Base Information

• Chemical Name: [1,1'-Biphenyl]-2-amine, 2',4',6'-trimethyl-
• CAS No.: 25627-20-7
• Molecular Formula: C₁₅H₁₇N
• Molecular Weight: 211.307
• Mol file: 25627-20-7.mol

Synonyms:mesitylaniline;2,6-DIHYDRO-2,2,4-TRIMETHYL-6-QUINOLONE;2'-Amino-2,4,6-trimethylbiphenyl;2',4',6'-trimethyl-biphenyl-2-ylamine;2'-Amino-2,4,6-trimethyl-biphenyl;

Chemical Property of [1,1'-Biphenyl]-2-amine, 2',4',6'-trimethyl-

Chemical Property:

• Boiling Point: 314.9±11.0 °C(Predicted)
• PSA: 26.02000
• Density: 1.026±0.06 g/cm3(Predicted)
• LogP: 4.44220

Purity/Quality:

99% ^*data from raw suppliers

2-(2,4,6-trimethylphenyl)aniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [1,1'-Biphenyl]-2-amine, 2',4',6'-trimethyl-

There total 8 articles about [1,1'-Biphenyl]-2-amine, 2',4',6'-trimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

1-iodo-2-(2′,4′,6′-trimethylphenyl)benzene → 2′,4′,6′-trimethyl-[1,1′-biphenyl]-2-amine (25627-20-7)

Guidance literature:

1-iodo-2-(2′,4′,6′-trimethylphenyl)benzene; With n-butyllithium; at 0 ℃;

With 4-toluenesulfonyl azide;

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1021/om3000289

Reference yield: 51.0%

2-azido-2',4',6'-trimethylbiphenyl (65753-85-7) → 2′,4′,6′-trimethyl-[1,1′-biphenyl]-2-amine (25627-20-7) + 1,2,4-trimethylcarbazole (97218-74-1)

Guidance literature:

With aluminium trichloride; In dichloromethane; Ambient temperature;

DOI:10.1039/c39850000287

Reference yield: 5.0%

2-azido-2',4',6'-trimethylbiphenyl (65753-85-7) → 2′,4′,6′-trimethyl-[1,1′-biphenyl]-2-amine (25627-20-7) + 1,2,4-trimethylcarbazole (97218-74-1) + 2-amino-5-(trifluoromethylsulphonyloxy)-2',4',6'-trimethylbiphenyl (106822-88-2)

Guidance literature:

With trifluorormethanesulfonic acid; In dichloromethane; Ambient temperature;

upstream raw materials:

2,4,6-trimethyl-2'-nitro-1,1'-biphenyl

trifluorormethanesulfonic acid

2-azido-2',4',6'-trimethylbiphenyl

mesitylboronic acid

Downstream raw materials:

2-methyl-8-(2,4,6-trimethyl-phenyl)-quinolin-4-ol

4-chloro-2-methyl-8-(2,4,6-trimethyl-phenyl)-quinoline

2'.4'.6'-Trimethyl-biphenyl-2-sulfonylchlorid