1,2-Cyclododecanediol

Base Information

• Chemical Name: 1,2-Cyclododecanediol
• CAS No.: 15199-41-4
• Molecular Formula: C12H24O2
• Molecular Weight: 200.321
• Hs Code.: 2906199090
• European Community (EC) Number: 239-256-5
• DSSTox Substance ID: DTXSID00934391
• Nikkaji Number: J179.397G
• Mol file: 15199-41-4.mol

Synonyms:1,2-Cyclododecanediol;Cyclododecane-1,2-diol;15199-41-4;EINECS 239-256-5;SCHEMBL560334;HAMFVYJFVXTJCJ-UHFFFAOYSA-;DTXSID00934391;1,2-Cyclododecanediol(cis+ trans);MFCD01321150;AKOS024332884;CS-0447144;T70323

Chemical Property of 1,2-Cyclododecanediol

Chemical Property:

• Vapor Pressure: 6.04E-06mmHg at 25°C
• Melting Point: 121.0 to 125.0 °C
• Refractive Index: 1.477
• Boiling Point: 339.7 °C at 760 mmHg
• Flash Point: 158.2 °C
• PSA: 40.46000
• Density: 0.968 g/cm³
• LogP: 2.62280
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 200.177630004
• Heavy Atom Count: 14
• Complexity: 120

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,2-Cyclododecanediol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCCCCC(C(CCCC1)O)O

Technology Process of 1,2-Cyclododecanediol

There total 10 articles about 1,2-Cyclododecanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

cis-cyclododecene (1129-89-1) → cyclododecane-1,2-diol (15199-41-4)

Guidance literature:

With cethyltrimethylammonium permanganate; In dichloromethane; at 25 ℃; Rate constant;

DOI:10.1021/jo00272a051

Reference yield:

cyclododecene (1501-82-2) → cyclododecane-1,2-dione (3008-41-1) + cyclododecane-1,2-diol (15199-41-4) + 1,2-epoxycyclododecane (286-99-7)

Guidance literature:

With tetrakis-1,3,5,7-(4-phosphonophenyl)adamantane octa-Na salt; dihydrogen peroxide; ortho-tungstic acid; In acetonitrile; at 70 ℃; for 5h;

DOI:10.1002/adsc.200404207

Reference yield:

cyclododecane (294-62-2) → cyclododecanol (1724-39-6) + cyclododecane-1,2-dione (3008-41-1) + cyclododecane-1,2-diol (15199-41-4) + cyclododecanone (830-13-7)

Guidance literature:

With dihydrogen peroxide; In water; acetonitrile; at 99.84 ℃; for 24h;

DOI:10.1016/j.apcata.2010.08.007

upstream raw materials:

(E)-Cyclododecen

trioxo(N-tert-butylimido)osmium(VIII)

cis-cyclododecene

cyclododecene

Downstream raw materials:

dodecanedial

1,12-dodecanedioic acid

1,2-bis-[3-(3,5-Di-t-butyl-4-hydroxyphenyl)propionyloxy]cyclododecane

Refernces

• 1、 Selvaraj,Park. "Highly selective synthesis of cyclododecanone over mesostructured VSBA-15 catalysts". . p. 22 - 30. Retrieved 2010.
• 2、 Freeman, Fillmore,Kappos, John C.. "Permanganate Ion Oxidations. 19. Hexadecyltrimethylammonium Permanganate Oxidation of Cycloalkenes". . p. 2730 - 2734. Retrieved 2007/10/02.