1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxaMide

Base Information

Chemical Name:1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxaMide
CAS No.:256376-62-2
Molecular Formula:C14H11FN4O
Molecular Weight:270.266
Hs Code.:2933990090
European Community (EC) Number:854-319-2
UNII:5GN35FMT7H
DSSTox Substance ID:DTXSID80462389
Nikkaji Number:J1.500.682J
Wikidata:Q82286919
Mol file:256376-62-2.mol

Synonyms:1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide;256376-62-2;1-[(2-FLUOROPHENYL)METHYL]PYRAZOLO[3,4-B]PYRIDINE-3-CARBOXAMIDE;1H-Pyrazolo[3,4-b]pyridine-3-carboxamide, 1-[(2-fluorophenyl)methyl]-;5GN35FMT7H;C14H11FN4O;SCHEMBL4929205;DTXSID80462389;GWDSAMDSGSEPRH-UHFFFAOYSA-N;F11567;A911342;1-[(2-fluorophenyl)methyl]pyrazolo[3, 4-b]pyridine-3-carboxamide;1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-3-carboxamide

Suppliers and Price of 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxaMide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide 95+%
1g
$ 699.00

Chemenu
1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide 95%
1g
$ 660.00

Total 14 raw suppliers

Chemical Property of 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxaMide

Chemical Property:

Boiling Point:533.5±45.0 °C(Predicted)
PKA:14.57±0.30(Predicted)
PSA：74.79000
Density:1.42±0.1 g/cm3(Predicted)
LogP:2.60180
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:270.09168915
Heavy Atom Count:20
Complexity:367

Purity/Quality:

99.9% ^*data from raw suppliers

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)CN2C3=C(C=CC=N3)C(=N2)C(=O)N)F

Technology Process of 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxaMide

There total 6 articles about 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxaMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 256376-59-7
ethyl 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylate

: 256376-62-2
1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide

Guidance literature:: With ammonia; In methanol; at 20 ℃; for 48h;
DOI:10.1016/S0960-894X(01)00073-7 DOI:10.1016/S0968-0896(02)00034-2

Reference yield:

: 256504-39-9
ethyl 5-amino-1-(2-fluorobenzyl)-1H-pyrazole-3-carboxylate

: 256376-62-2
1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: TFA / dioxane / 72 h / Heating

2: 100 percent / NH₃ / methanol / 48 h / 20 °C

With ammonia; trifluoroacetic acid; In 1,4-dioxane; methanol;
DOI:10.1016/S0960-894X(01)00073-7 DOI:10.1016/S0968-0896(02)00034-2

Reference yield:

: 51859-98-4
(2-fluorobenzyl)hydrazine

: 256376-62-2
1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: TFA / dioxane / 8 h / Heating

2: TFA / dioxane / 72 h / Heating

3: 100 percent / NH₃ / methanol / 48 h / 20 °C

With ammonia; trifluoroacetic acid; In 1,4-dioxane; methanol;
DOI:10.1016/S0960-894X(01)00073-7 DOI:10.1016/S0968-0896(02)00034-2