N-(4-Aminophenyl)-2-(dimethylamino)acetamide

Base Information

Chemical Name:N-(4-Aminophenyl)-2-(dimethylamino)acetamide
CAS No.:25786-09-8
Molecular Formula:C10H15N3O
Molecular Weight:193.249
Hs Code.:2924299090
European Community (EC) Number:853-542-2
DSSTox Substance ID:DTXSID30588482
Wikidata:Q82481170
Mol file:25786-09-8.mol

Synonyms:25786-09-8;N-(4-Aminophenyl)-2-(dimethylamino)acetamide;N~1~-(4-AMINOPHENYL)-N~2~,N~2~-DIMETHYLGLYCINAMIDE;n1-(4-aminophenyl)-n2,n2-dimethylglycinamide;N-(4-aminophenyl)-N2,N2-dimethylglycinamide;N-(4-aminophenyl)-N~2~,N~2~-dimethylglycinamide;SCHEMBL1409656;DTXSID30588482;QACLSTIJJPYRJI-UHFFFAOYSA-N;BBL011779;MFCD09733249;STK727184;AKOS000113372;MCULE-2636245261;4-dimethylaminomethylcarbonylamino-aniline;DA-43020;VS-03032;CS-0118539;EN300-96493;n-(4-amino-phenyl)-2-dimethylamino-acetamide

Suppliers and Price of N-(4-Aminophenyl)-2-(dimethylamino)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(4-aminophenyl)-N2,N2-dimethylglycinamide
5g
$ 195.00

ChemBridge Corporation
N~1~-(4-aminophenyl)-N~2~,N~2~-dimethylglycinamide 95%
1 g
$ 23.00

American Custom Chemicals Corporation
N-1-(4-AMINOPHENYL)-N-2,N-2-DIMETHYLGLYCINAMIDE 95.00%
5MG
$ 495.77

AK Scientific
N-(4-Aminophenyl)-2-(dimethylamino)acetamide
250mg
$ 171.00

Total 6 raw suppliers

Chemical Property of N-(4-Aminophenyl)-2-(dimethylamino)acetamide

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Melting Point:87 - 92°C
Boiling Point:304.059oC at 760 mmHg
PKA:14.09±0.70(Predicted)
Flash Point:137.691oC
PSA：58.36000
Density:1.171g/cm3
LogP:1.42310
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:193.121512110
Heavy Atom Count:14
Complexity:186

Purity/Quality:

97% ^*data from raw suppliers

N-(4-aminophenyl)-N2,N2-dimethylglycinamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CC(=O)NC1=CC=C(C=C1)N

Technology Process of N-(4-Aminophenyl)-2-(dimethylamino)acetamide

There total 6 articles about N-(4-Aminophenyl)-2-(dimethylamino)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 25786-08-7
2-dimethylamino-N-(4-nitro-phenyl)-acetamide

: 25786-09-8
N-(4-amino-phenyl)-2-dimethylamino-acetamide

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethyl acetate; under 1810.07 - 1965.21 Torr;
DOI:10.1016/j.ejmech.2014.02.018

Reference yield:

: [4-(2-Dimethylamino-acetylamino)-phenyl]-carbamic acid tert-butyl ester

: 25786-09-8
N-(4-amino-phenyl)-2-dimethylamino-acetamide

Guidance literature:: [4-(2-Dimethylamino-acetylamino)-phenyl]-carbamic acid tert-butyl ester; With trifluoroacetic acid; In dichloromethane; at 20 ℃; Cooling with ice;

With sodium hydrogencarbonate; In dichloromethane; water;

Reference yield:

: 17329-87-2
2-chloro-N-(4-nitro-phenyl)-acetamide

: 25786-09-8
N-(4-amino-phenyl)-2-dimethylamino-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / methanol / 0 - 20 °C

2: 84 percent / ammonium formate; Pd/C / dimethylformamide / 16 h / 20 °C

With palladium on activated charcoal; ammonium formate; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/ja0661919