2-Propenal, 3-(3-hydroxyphenyl)-, (2E)-

Base Information

• Chemical Name: 2-Propenal, 3-(3-hydroxyphenyl)-, (2E)-
• CAS No.: 26231-89-0
• Molecular Formula: C9H8O2
• Molecular Weight: 148.161
• Mol file: 26231-89-0.mol

Synonyms:2-Propenal,3-(3-hydroxyphenyl);(E)-3-(3-hydroxyphenyl)acrylaldehyde;3-hydroxycinnamaldehyde;m-Hydroxyzimtaldehyd;2-Propenal,3-(3-hydroxyphenyl)-,(2E);m-hydroxycinnamaldehyde;meta-hydroxycinnamaldehyde;

Chemical Property of 2-Propenal, 3-(3-hydroxyphenyl)-, (2E)-

Chemical Property:

• PSA: 37.30000
• LogP: 1.60430

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Propenal, 3-(3-hydroxyphenyl)-, (2E)-

There total 6 articles about 2-Propenal, 3-(3-hydroxyphenyl)-, (2E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

acetaldehyde (75-07-0,9002-91-9) + meta-hydroxybenzaldehyde (100-83-4) → (E)-3-(3-hydroxyphenyl)acrylaldehyde (26231-89-0)

Guidance literature:

With sodium hydroxide; In ethanol; water; at 0 - 10 ℃;

DOI:10.1016/j.bmcl.2014.04.105

Reference yield: 53.0%

acrylaldehyde diethyl acetal (3054-95-3) + 3-Iodophenol (626-02-8) → (E)-3-(3-hydroxyphenyl)acrylaldehyde (26231-89-0)

Guidance literature:

With potassium chloride; tetrabutylammonium acetate; palladium diacetate; potassium carbonate; at 90 ℃; for 5h;

DOI:10.1016/j.ejmech.2022.114151

Reference yield: 43.0%

vinyl acetate (108-05-4,9003-20-7) + meta-hydroxybenzaldehyde (100-83-4) → (E)-3-(3-hydroxyphenyl)acrylaldehyde (26231-89-0)

Guidance literature:

With water; potassium carbonate; In acetonitrile; for 40h; Heating;

DOI:10.1081/SCC-120030309

upstream raw materials:

acetaldehyde

meta-hydroxybenzaldehyde

trans-3-(3-hydroxy-1-propenyl)phenol

vinyl acetate

Downstream raw materials:

(R)-3-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)-3-(3-hydroxyphenyl)propanenitrile

(R)-(4-(1-(2-cyano-1-(3-hydroxyphenyl)ethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate

(R)-(4-(1-(1-(3-hydroxyphenyl)-3-oxopropyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate

1-(4-hydroxyphenyl)-7-(3-hydroxyphenyl)-1,4,6-heptatrien-3-one