Piperazine, 1-(4-aminophenyl)-4-(2-furanylcarbonyl)-

Base Information

Chemical Name:Piperazine, 1-(4-aminophenyl)-4-(2-furanylcarbonyl)-
CAS No.:262375-98-4
Molecular Formula:C15H17N3O2
Molecular Weight:271.319
Hs Code.:
DSSTox Substance ID:DTXSID30359058
Wikidata:Q82140055
Pharos Ligand ID:53CKTRQQUW1N
ChEMBL ID:CHEMBL1564800
Mol file:262375-98-4.mol

Synonyms:262375-98-4;Methanone, [4-(4-aminophenyl)-1-piperazinyl]-2-furanyl-;Piperazine, 1-(4-aminophenyl)-4-(2-furanylcarbonyl)-;SMR000144404;MLS000538367;CHEMBL1564800;DTXSID30359058;HMS2465D04;STK141124;AKOS000104413;4-[4-(2-furoyl)-1-piperazinyl]aniline;BB 0245662;MLS000538367-02;SR-01000290091;SR-01000290091-1;[4-(4-aminophenyl)piperazin-1-yl](furan-2-yl)methanone;[4-(4-Amino-phenyl)-piperazin-1-yl]-furan-2-yl -methanone;(4-(4-Aminophenyl)piperazin-1-yl)(furan-2-yl)methanone, AldrichCPR

Suppliers and Price of Piperazine, 1-(4-aminophenyl)-4-(2-furanylcarbonyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Piperazine, 1-(4-aminophenyl)-4-(2-furanylcarbonyl)-

Chemical Property:

PSA：62.71000
LogP:2.40830
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:271.132076794
Heavy Atom Count:20
Complexity:334

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1C2=CC=C(C=C2)N)C(=O)C3=CC=CO3

Technology Process of Piperazine, 1-(4-aminophenyl)-4-(2-furanylcarbonyl)-

There total 3 articles about Piperazine, 1-(4-aminophenyl)-4-(2-furanylcarbonyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 262375-97-3
furan-2-yl-[4-(4-nitro-phenyl)-piperazin-1-yl]-methanone

: 262375-98-4
[4-(4-amino-phenyl)-piperazin-1-yl]-furan-2-yl-methanone

Guidance literature:: With hydrogenchloride; tin; In chloroform; water; Reflux;
DOI:10.1016/j.bmcl.2015.01.004

Reference yield:

: 350-46-9,178603-76-4
4-Fluoronitrobenzene

: 262375-98-4
[4-(4-amino-phenyl)-piperazin-1-yl]-furan-2-yl-methanone

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile / 2 h / Reflux

2: palladium 10% on activated carbon; hydrogen / methanol / 4 h / 20 °C / 2585.81 Torr

With palladium 10% on activated carbon; hydrogen; In methanol; acetonitrile;
DOI:10.1016/j.ejmech.2014.07.001

Reference yield:

: 40172-95-0
N-(furan-2-carbonyl)piperazine

: 262375-98-4
[4-(4-amino-phenyl)-piperazin-1-yl]-furan-2-yl-methanone

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile / 2 h / Reflux

2: palladium 10% on activated carbon; hydrogen / methanol / 4 h / 20 °C / 2585.81 Torr

With palladium 10% on activated carbon; hydrogen; In methanol; acetonitrile;
DOI:10.1016/j.ejmech.2014.07.001