3-(3,4-DICHLOROPHENYL)PROPIONIC ACID

Base Information

• Chemical Name: 3-(3,4-DICHLOROPHENYL)PROPIONIC ACID
• CAS No.: 25173-68-6
• Molecular Formula: C9H8Cl2O2
• Molecular Weight: 219.067
• Hs Code.: 2916399090
• Mol file: 25173-68-6.mol

Synonyms:Hydrocinnamicacid, 3,4-dichloro- (6CI,7CI,8CI);3,4-Dichloro-b-phenylpropionic acid;3-(3,4-Dichlorophenyl)propanoicacid;3-(3,4-Dichlorophenyl)propionic acid;b-(3,4-Dichlorophenyl)propionic acid;

Chemical Property of 3-(3,4-DICHLOROPHENYL)PROPIONIC ACID

Chemical Property:

• Melting Point: 97 °C
• Boiling Point: 339.2 °C at 760 mmHg
• PKA: 4.52±0.10(Predicted)
• Flash Point: 158.9 °C
• PSA: 37.30000
• Density: 1.392 g/cm³
• LogP: 3.01060
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

3-(3,4-Dichlorophenyl)propanoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(3,4-DICHLOROPHENYL)PROPIONIC ACID

There total 11 articles about 3-(3,4-DICHLOROPHENYL)PROPIONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3,4-dichlorocinnamic acid (1202-39-7) → 3(3,4-dichlorophenyl)propanoic acid (25173-68-6)

Guidance literature:

With platinum(IV) oxide; hydrogen; under 2585.7 Torr;

DOI:10.1021/jm00119a008

Reference yield: 43.0%

methyl 3‐(3,4‐dichlorophenyl)propanoate (115706-17-7) → 3(3,4-dichlorophenyl)propanoic acid (25173-68-6)

Guidance literature:

With sodium hydroxide; for 2h; Heating;

DOI:10.1021/jm00119a008

Reference yield:

hexahydrated nickel chloride + 3,4-Dichlorocinnamic acid (7312-27-8) → 3(3,4-dichlorophenyl)propanoic acid (25173-68-6)

Guidance literature:

With hydrogenchloride; sodium borohydrid; In methanol; aqueous potassium hydroxide;

upstream raw materials:

1-(3,4-dichlorophenyl)propan-1-one

3,4-dichlorocinnamic acid

3,4-Dichlorocinnamic acid

methyl 3‐(3,4‐dichlorophenyl)propanoate

Downstream raw materials:

3-(3 ,4-dichlorophenyl)propan-1-ol

3-(3,4-dichlorophenyl)propionamide

(S)-2-[3-(3,4-Dichloro-phenyl)-propionylamino]-N-(2-oxo-tetrahydro-thiophen-3-yl)-3-phenyl-propionamide

methyl 3‐(3,4‐dichlorophenyl)propanoate