7312-27-8

Basic information

• Product Name: 3,4-Dichlorocinnamic acid
• Synonyms: (E)-3-(3,4-Dichlorophenyl)propenoic acid;3,4-Dichloro-trans-cinnamic acid;trans-3,4-Dichlorocinnamic acid
• CAS NO: 7312-27-8
• Molecular Formula: C₉H₆Cl₂O₂
• Molecular Weight: 217.05
• Mol File: 7312-27-8.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,4-Dichlorocinnamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Dichlorocinnamic acid(7312-27-8)
• EPA Substance Registry System: 3,4-Dichlorocinnamic acid(7312-27-8)

Safety Data

• Hazardous Substances Data: 7312-27-8(Hazardous Substances Data)

Usage

General Description

3,4-Dichlorocinnamic acid is a chemical compound with the molecular formula C9H6Cl2O2. It is a derivative of cinnamic acid, and its structure consists of a benzene ring with two chlorine atoms and a carboxylic acid group attached at the 3 and 4 positions, respectively. 3,4-Dichlorocinnamic acid is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its diverse applications include its use as a food flavoring agent, in the production of UV stabilizers, and in the preparation of perfumes and fragrances. Additionally, 3,4-Dichlorocinnamic acid possesses potential biological activities, such as antifungal and antibacterial properties, making it a compound of interest for further research in the fields of medicine and agriculture.

Upstream product

• 95-76-1 m,p-dichloroaniline 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 6287-38-3 3,4-dichlorobenzaldehyde 
• 108-24-7 acetic anhydride 
• 79-11-8 chloroacetic acid 
• 141-82-2 malonic acid 
• 20595-52-2 (2Z)-3-(3,4-dichlorophenyl)acrylic acid 
• 33224-65-6 3,4-dichloro-benzaldehyde diethylacetal 

Downstream Products

• 2039-83-0 3,4-dichlorostyrene 
• 130553-83-2 (E)-3-(3,4-Dichloro-phenyl)-N-methyl-N-((1R,2S)-2-pyrrolidin-1-yl-cyclohexyl)-acrylamide 
• 111544-30-0 (E)-3-(6-Chloro-benzo[1,3]dioxol-5-yl)-acrylic acid; compound with (E)-3-(3,4-dichloro-phenyl)-acrylic acid 
• 64024-24-4 3,3',4,4'-Tetrachlor-β-truxinsaeure 
• 141824-01-3 8-[(E)-3,4-Dichlorostyryl]-1,3-dipropylxanthine 
• 100098-59-7 (E)-3,4-dichloro-N-(2-hydroxy-1,1-dimethylethyl) cinnamamide 
• 100098-74-6 (E)-2-(3,4-dichlorostyryl)-4,4-dimethyl-2-oxazoline hydrochloride 
• 80272-06-6 3-(3',4'-dichlorophenyl)-3-phenylpropanoic acid 
• 82475-75-0 methyl 3-(3,4-dichlorophenyl)-2-propenoate 
• 25157-66-8 4-(3,4-dichlorophenyl)butanoic acid 
• 25173-68-6 3(3,4-dichlorophenyl)propanoic acid 
• 732189-89-8 4-(3,4-dichlorophenyl)butan-1-amine 
• 76706-60-0 3-(3,4-dichlorophenyl)propan-1-amine 
• 39960-04-8 3-(3,4-dichlorophenyl)propionamide 

Relevant articles and documents

Visible-light promoted oxidative cyclization of cinnamic acid derivatives using xanthone as the photocatalyst

We have developed an efficient photocatalytic synthesis of coumarin derivativesviaa tandem double bond isomerization/oxidative cyclization of cinnamic acids. Inexpensive and stable xanthone was used as the photocatalyst, and readily available Selectfluor was used as the oxidant. This method tolerates a wide range of functional groups and offers excellent chemical yields in general. Besides, the photocatalytic oxidative cyclization of cinnamic acid esters gives dimerized lignan-type products.

Cinnamic acid derivative and preparation method and application thereof

The invention provides a cinnamic acid derivative. The cinnamic acid derivative is of the structure as shown in the formula I. The invention also provides two methods for preparing the cinnamic acid derivative. The two methods depend on a single bond or double bonds in the structure shown in the formula I. The invention further provides a pesticide. The pesticide comprises the cinnamic acid derivative. In addition, the invention provides a sterilization method. The sterilization method includes the step of applying the cinnamic acid derivative or the pesticide to crops. The crops include rice,wheat, fruit trees and vegetables. The low-toxicity, low-residue-content and high-activity environment-friendly cinnamic acid derivative is developed, and the cinnamic acid derivative pesticide can replace traditional high-toxicity and high-residue-content pesticides.

β-alanine-DBU: A highly efficient catalytic system for knoevenagel-doebner reaction under mild conditions

A mild and efficient Knoevenagel-Doebner reaction from malonic acid and a wide range of aldehydes was catalyzed by a catalytic system consisting of β-alanine and 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU), affording the corresponding (E)-α,β-unsaturated carboxylic acids in good to excellent yields and with high stereoselectivity. The advantage of the method is that the reaction could proceed smoothly at ambient temperature so that it can tolerate a variety of functional groups and avoid unnecessary side reactions. Copyright