4-BroMo-2-diethoxyMethyl-furan

Base Information

• Chemical Name: 4-BroMo-2-diethoxyMethyl-furan
• CAS No.: 27065-51-6
• Molecular Formula: C9H13BrO3
• Molecular Weight: 249.10200
• Mol file: 27065-51-6.mol

Synonyms:5-bromo-2-chlorobenzyl bromide;1-bromo-3-bromomethyl-4-chloro-benzene;Benzene,4-bromo-2-(bromomethyl)-1-chloro;4-Bromfuran-2-carbaldehyd-diethylacetal;4-Bromfurfural-diaethylacetal;4-bromo-2-(diethoxymethyl)furan;4-bromo-2-bromomethyl-1-chloro-benzene;2-(diethoxymethyl)-4-bromofuran;4-bromofurfural diethyl acetal;

Chemical Property of 4-BroMo-2-diethoxyMethyl-furan

Chemical Property:

• Vapor Pressure: 0.235mmHg at 25°C
• Boiling Point: 213.792oC at 760 mmHg
• Flash Point: 83.099oC
• PSA: 31.60000
• Density: 1.352g/cm3
• LogP: 3.11370

Purity/Quality:

99% ^*data from raw suppliers

4-Bromo-2-(diethoxymethyl)furan 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BroMo-2-diethoxyMethyl-furan

There total 7 articles about 4-BroMo-2-diethoxyMethyl-furan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

4,5-dibromo-2-(diethoxymethyl)-furan (4828-13-1) → 2-(diethoxymethyl)-4-bromofuran (27065-51-6)

Guidance literature:

With n-butyllithium; In diethyl ether; -78 deg C up to 0 deg C within 2 h;

DOI:10.1016/S0040-4020(01)85090-0

Reference yield:

4-bromo-2-furancarbaldehyde (21921-76-6) + orthoformic acid triethyl ester (122-51-0) → 2-(diethoxymethyl)-4-bromofuran (27065-51-6)

Guidance literature:

With pyridinium p-toluenesulfonate; In ethanol;

DOI:10.1016/S0040-4020(01)00175-2

Reference yield:

orthoformic acid triethyl ester (122-51-0) → 2-(diethoxymethyl)-4-bromofuran (27065-51-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / ammonium chloride / ethanol / 16 h / Heating

2: 73 percent / n-butyllithium / diethyl ether; hexane / 1 h / -78 °C

With n-butyllithium; ammonium chloride; In diethyl ether; ethanol; hexane;

DOI:10.1016/j.tet.2005.03.016

upstream raw materials:

4,5-dibromo-2-(diethoxymethyl)-furan

4-bromo-2-furancarbaldehyde

orthoformic acid triethyl ester

furfural

Downstream raw materials:

methyl (E)-2,4-di(methoxymethoxy)-6-methyl-3-<3-methyl-6-(furanyl-5-carboxaldehyde)-2-hexenyl>-benzoate

4-methylsulfanyl-2-furaldehyde

N-benzyl-N-[4-(methylsulfanyl)-2-furyl]methylamine

methyl (E)-4-hydroxy-2-methoxymethoxy-6-methyl-3<3-methyl-6-<5-(2-methyl-1-propenyl)-3-furanyl>-2-hexenyl>-benzoate