2,4'-Diamino[sulfonylbisbenzene]

Base Information

• Chemical Name: 2,4'-Diamino[sulfonylbisbenzene]
• CAS No.: 27147-69-9
• Molecular Formula: C₁₂H₁₂N₂O₂S
• Molecular Weight: 248.305
• Hs Code.: 2921590090
• Mol file: 27147-69-9.mol

Synonyms:o,p'-Sulfonyldianiline;(2-amino-phenyl)-(4-amino-phenyl)-sulfone;Benzenamine,2-[(4-aminophenyl)sulfonyl];2,4--sulfonyldianiline;2.4'-Sulfonylbis(benzolamin);2-(4-aminophenylsulfonyl)aniline;

Chemical Property of 2,4'-Diamino[sulfonylbisbenzene]

Chemical Property:

• Melting Point: 117 °C
• Boiling Point: 505.7±35.0 °C(Predicted)
• PKA: 0.95±0.10(Predicted)
• PSA: 94.56000
• Density: 1.361±0.06 g/cm3(Predicted)
• LogP: 3.92700

Purity/Quality:

> 95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2,4''-Diaminophenyl Sulfone is used in biological studies as dapsone leprosy inhibitor. 2,4''-Diaminophenyl Sulfone is also an impurity of dapsone (D193250) which is an antibacterial used in the treatment of dermatitis herpetiformis.

Technology Process of 2,4'-Diamino[sulfonylbisbenzene]

There total 3 articles about 2,4'-Diamino[sulfonylbisbenzene] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-nitrophenyl bromide (577-19-5) + 4-acetamidobenzenesulfinic acid (710-24-7) → (2-amino-phenyl)-(4-amino-phenyl)-sulfone (27147-69-9)

Guidance literature:

With 2-ethoxy-ethanol; potassium acetate; beim Erwaermen des Reaktionsprodukts mit Eisen-Pulver und verd. wss.Essigsaeure und Erhitzen des Reaktionsprodukts mit wss.Salzsaeure;

DOI:10.1021/ja01852a038

Reference yield:

acetic acid-[4-(2-amino-benzenesulfonyl)-anilide] (18514-07-3) → (2-amino-phenyl)-(4-amino-phenyl)-sulfone (27147-69-9)

Guidance literature:

With hydrogenchloride;

Reference yield:

→ (2-amino-phenyl)-(4-amino-phenyl)-sulfone (27147-69-9)

Guidance literature:

Acetamid V, conc. HCl, Δ;

DOI:10.1002/jps.2600661217

upstream raw materials:

2-nitrophenyl bromide

4-acetamidobenzenesulfinic acid

acetic acid-[4-(2-amino-benzenesulfonyl)-anilide]