tert-Butyl[(2-iodophenyl)methoxy]dimethylsilane

Base Information

Chemical Name:tert-Butyl[(2-iodophenyl)methoxy]dimethylsilane
CAS No.:271769-81-4
Molecular Formula:C13H21IOSi
Molecular Weight:348.299
Hs Code.:
DSSTox Substance ID:DTXSID40590839
Nikkaji Number:J1.569.331B
Wikidata:Q82484464

Synonyms:271769-81-4;tert-Butyl[(2-iodophenyl)methoxy]dimethylsilane;SCHEMBL6438766;DTXSID40590839;2-Iodobenzyl alcohol, TBDMS derivative;tert-butyl((2-iodobenzyl)oxy)dimethylsilane;2-Iodobenzyl alcohol, tert-butyldimethylsilyl ether;(1,1-Dimethylethyl)[(2-iodophenyl)methoxy]dimethylsilane

Suppliers and Price of tert-Butyl[(2-iodophenyl)methoxy]dimethylsilane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-Butyl[(2-iodophenyl)methoxy]dimethylsilane

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:348.04064
Heavy Atom Count:16
Complexity:223

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)[Si](C)(C)OCC1=CC=CC=C1I

Technology Process of tert-Butyl[(2-iodophenyl)methoxy]dimethylsilane

There total 4 articles about tert-Butyl[(2-iodophenyl)methoxy]dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 5159-41-1
2-iodobenzyl alcohol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 271769-81-4
(1,1-dimethylethyl)[(2-iodophenyl)methoxy]dimethylsilane

Guidance literature:: With 1H-imidazole; dmap; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1021/jo0107296

Reference yield:

: 41879-37-2
t-butyldimethylsilyl amine

: 5159-41-1
2-iodobenzyl alcohol

: 271769-81-4
(1,1-dimethylethyl)[(2-iodophenyl)methoxy]dimethylsilane

Guidance literature:: In tetrahydrofuran; at 20 ℃; for 20h; Green chemistry;
DOI:10.1071/CH16097

Reference yield:

: 88-67-5
2-Iodobenzoic acid

: 271769-81-4
(1,1-dimethylethyl)[(2-iodophenyl)methoxy]dimethylsilane

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylsulfide borane complex / tetrahydrofuran / 16 h / 0 - 20 °C / Inert atmosphere

2: 1H-imidazole; dmap / N,N-dimethyl-formamide / 16 h / 20 °C / Inert atmosphere

With 1H-imidazole; dmap; dimethylsulfide borane complex; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/j.tetlet.2013.08.077