2,5-Pyrrolidinedione, 1-[(2,3-dihydroxy-5-nitrobenzoyl)oxy]-

Base Information

Chemical Name:2,5-Pyrrolidinedione, 1-[(2,3-dihydroxy-5-nitrobenzoyl)oxy]-
CAS No.:273204-52-7
Molecular Formula:C11H8N2O8
Molecular Weight:296.193
Hs Code.:
DSSTox Substance ID:DTXSID30476911
Nikkaji Number:J1.660.612J
Wikidata:Q82308840

Synonyms:273204-52-7;2,5-Pyrrolidinedione, 1-[(2,3-dihydroxy-5-nitrobenzoyl)oxy]-;DTXSID30476911

Suppliers and Price of 2,5-Pyrrolidinedione, 1-[(2,3-dihydroxy-5-nitrobenzoyl)oxy]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2,5-Pyrrolidinedione, 1-[(2,3-dihydroxy-5-nitrobenzoyl)oxy]-

Chemical Property:

XLogP3:0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:296.02806522
Heavy Atom Count:21
Complexity:471

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)N(C1=O)OC(=O)C2=C(C(=CC(=C2)[N+](=O)[O-])O)O

Technology Process of 2,5-Pyrrolidinedione, 1-[(2,3-dihydroxy-5-nitrobenzoyl)oxy]-

There total 3 articles about 2,5-Pyrrolidinedione, 1-[(2,3-dihydroxy-5-nitrobenzoyl)oxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 72517-20-5
2,3-dihydroxy-5-nitrobenzoic acid

: 273204-52-7
2,5-Dioxotetrahydro-1H-pyrrol-1-yl 2,3-dihydroxy-5-nitrobenzoate

Guidance literature:: With dicyclohexyl-carbodiimide; In tetrahydrofuran; at 4 ℃;
DOI:10.1002/(SICI)1521-3765(20000317)6:6<971::AID-CHEM971>3.0.CO;2-0

Reference yield:

: 877-22-5
3-methoxysalicylic acid

: 273204-52-7
2,5-Dioxotetrahydro-1H-pyrrol-1-yl 2,3-dihydroxy-5-nitrobenzoate

Guidance literature:: Multi-step reaction with 3 steps

1: 94 percent / aq. HNO₃; H₂SO₄ / CH₂Cl₂ / 3 h / 0 - 20 °C

2: 79 percent / aq. HBr / 4 h / 135 °C

3: 53 percent / DCC / tetrahydrofuran / 4 °C

With sulfuric acid; hydrogen bromide; nitric acid; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane; 1: Nitration / 2: demethylation / 3: Acylation;
DOI:10.1002/(SICI)1521-3765(20000317)6:6<971::AID-CHEM971>3.0.CO;2-0

Reference yield:

: 20718-78-9
2-Hydroxy-3-methoxy-5-nitrobenzoic acid

: 273204-52-7
2,5-Dioxotetrahydro-1H-pyrrol-1-yl 2,3-dihydroxy-5-nitrobenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / aq. HBr / 4 h / 135 °C

2: 53 percent / DCC / tetrahydrofuran / 4 °C

With hydrogen bromide; dicyclohexyl-carbodiimide; In tetrahydrofuran; 1: demethylation / 2: Acylation;
DOI:10.1002/(SICI)1521-3765(20000317)6:6<971::AID-CHEM971>3.0.CO;2-0