2,3-diphenylquinolizinium bromide

Base Information

• Chemical Name: 2,3-diphenylquinolizinium bromide
• CAS No.: 16171-40-7
• Molecular Formula: C21H16 N . Br
• Molecular Weight: 362.269
• Mol file: 16171-40-7.mol

Synonyms:2,3-Diphenylquinoliziniumbromide (7CI); Quinolizinium, 2,3-diphenyl-, bromide (8CI,9CI)

Chemical Property of 2,3-diphenylquinolizinium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3-diphenylquinolizinium bromide

There total 4 articles about 2,3-diphenylquinolizinium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

1-(2-ethoxy-2-oxoethyl)-2-methylpyridin-1-ium bromide (55814-02-3) + benzil (134-81-6) → 2,3-diphenylquinolizinium bromide (16171-40-7)

Guidance literature:

With sodium acetate; In acetone; for 2h; Heating;

Reference yield: 4.0%

2-methyl-1-(2-oxo-2-phenylethyl)pyridinium bromide (32896-98-3) + benzil (134-81-6) → 2-phenylindolizine (25379-20-8) + 2,3-diphenylquinolizinium bromide (16171-40-7)

Guidance literature:

With dibutylamine; In acetone; for 2h; Heating;

Reference yield:

α-picoline (109-06-8) + bromoacetic acid (79-08-3) + benzil (134-81-6) → 2,3-diphenylquinolizinium bromide (16171-40-7)

Guidance literature:

α-picoline; bromoacetic acid; With benzotriazol-1-ol; dacarbazine; Wang resin; In dichloromethane; N,N-dimethyl-formamide; at 0 - 20 ℃;

benzil; With triethylamine; In tetrahydrofuran; at 70 ℃; for 18h;

DOI:10.1021/ol035417z

upstream raw materials:

2-methyl-1-(2-oxo-2-phenylethyl)pyridinium bromide

benzil

1-(2-ethoxy-2-oxoethyl)-2-methylpyridin-1-ium bromide

α-picoline

Downstream raw materials:

1-piperidino-4-(4',5'-diphenyl-2'-pyridyl)-1,3-butadiene

Refernces

• 1、 Chinta Rao,Saha, Sanjay,Raolji, Gajendra B.,Patro, Balaram,Risbood, Prabhaker,Difilippantonio, Michael J.,Tomaszewski, Joseph E.,Malhotra, Sanjay V.. "Microwave assisted Westphal condensation and its application to synthesis of sempervirine and related compounds". supporting information. p. 487 - 490. Retrieved 2013/02/25.