3-amino-4-(1-piperidinyl)-benzonitrile

Base Information

Chemical Name:3-amino-4-(1-piperidinyl)-benzonitrile
CAS No.:27429-67-0
Molecular Formula:C12H15N3
Molecular Weight:201.271
Hs Code.:
Mol file:27429-67-0.mol

Synonyms:3-Amino-4-piperidinobenzonitril;3-Amino-4-piperidino-benzonitril;3-Amino-4-piperidin-1-yl-benzonitrile;

Suppliers and Price of 3-amino-4-(1-piperidinyl)-benzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Amino-4-(piperidin-1-yl)benzonitrile 97%
1g
$ 474.00

A1 Biochem Labs
3-Amino-4-(1-piperidinyl)-benzonitrile 95%
5 g
$ 1100.00

Total 6 raw suppliers

Chemical Property of 3-amino-4-(1-piperidinyl)-benzonitrile

Chemical Property:

Melting Point:56 °C
PSA：53.05000
LogP:2.77698

Purity/Quality:

98%+ ^*data from raw suppliers

3-Amino-4-(piperidin-1-yl)benzonitrile 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-amino-4-(1-piperidinyl)-benzonitrile

There total 6 articles about 3-amino-4-(1-piperidinyl)-benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

: 32117-03-6
3-nitro-4-(piperidin-1-yl)benzonitrile

: 27429-67-0
3-amino-4-(piperidin-1-yl)benzonitrile

Guidance literature:: With 10% Pt/activated carbon; hydrogen; In ethanol; at 25 ℃;

Reference yield:

: 110-89-4
piperidine

: 27429-67-0
3-amino-4-(piperidin-1-yl)benzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: sodium acetate; alcohol

2: tin dichloride; fuming hydrochloric acid

With hydrogenchloride; ethanol; sodium acetate; tin(ll) chloride;

Reference yield:

: 939-80-0
4-chloro-3-nitrobenzonitrile

: 27429-67-0
3-amino-4-(piperidin-1-yl)benzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 0 - 80 °C

2: zinc; ammonium chloride / ethanol / 16 h / Inert atmosphere; Reflux

With potassium carbonate; ammonium chloride; zinc; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bioorg.2021.105244