Phosphine oxide, bis(2-phenylethyl)-

Base Information

• Chemical Name: Phosphine oxide, bis(2-phenylethyl)-
• CAS No.: 27440-52-4
• Molecular Formula: C16H19OP
• Molecular Weight: 258.3
• DSSTox Substance ID: DTXSID50459165
• Wikidata: Q82282822
• Mol file: 27440-52-4.mol

Synonyms:Phosphine oxide, bis(2-phenylethyl)-;27440-52-4;SCHEMBL7278104;bis(2-phenylethyl)phosphine oxide;DTXSID50459165;oxo-bis(2-phenylethyl)phosphanium;GTRHZZXHJDETGQ-UHFFFAOYSA-N;Di-(2-phenylethyl)phosphine Oxide

Chemical Property of Phosphine oxide, bis(2-phenylethyl)-

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 6
• Exact Mass: 257.109527191
• Heavy Atom Count: 18
• Complexity: 216

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CC[P+](=O)CCC2=CC=CC=C2

Technology Process of Phosphine oxide, bis(2-phenylethyl)-

There total 21 articles about Phosphine oxide, bis(2-phenylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

bis(2-phenethyl)phosphine (93017-30-2) → bis(2-phenylethyl)phosphine oxide (27440-52-4)

Guidance literature:

With oxygen; In diethyl ether; Heating;

Reference yield: 83.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) → Di-(2-phenylethyl)phosphinic Acid (14561-21-8) + bis(2-phenylethyl)phosphine oxide (27440-52-4) + tri(2-phenylethyl)phosphine oxide (29701-83-5)

Guidance literature:

With phosphorus; potassium hydroxide; hydroquinone; In water; dimethyl sulfoxide; for 0.0666667h; microwave irradiation;

DOI:10.1134/S1070363207030140

Reference yield: 76.0%

bis(2-phenethyl)phosphine (93017-30-2) + 4-vinyloxyethyl-1,4-perhydrothiazine 1-oxide (108099-44-1) → bis(2-phenylethyl)phosphine oxide (27440-52-4) + 4-[2-(2-Diphenethylphosphanyl-ethoxy)-ethyl]-thiomorpholine 1-oxide + 4-{2-[2-(Diphenethyl-phosphinoyl)-ethoxy]-ethyl}-thiomorpholine 1-oxide

Guidance literature:

With 2,2'-azobis(isobutyronitrile); at 80 ℃; for 5h; Yield given. Title compound not separated from byproducts;

upstream raw materials:

styrene

1,1-Diphenylethylene

bis(2-phenethyl)phosphine

2-methyl-5-vinylpyridine

Downstream raw materials:

5-[2-(Diphenethyl-phosphinoyl)-ethyl]-2-methyl-pyridine

Di-(2-phenylethyl)phosphinic Acid