2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)- (9CI)

Base Information

Chemical Name:2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)- (9CI)
CAS No.:274901-37-0
Molecular Formula:C7H9ClN2O
Molecular Weight:172.614
Hs Code.:
Mol file:274901-37-0.mol

Synonyms:1-chloroacetyl-2-cyanopyrrolidine;1-(chloroacetyl)pyrrolidine-2-carbonitrile;2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-;1-(2-chloroacetyl)pyrrolidine-2-carbonitrile;

Suppliers and Price of 2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile 97%
1g
$ 480.00

Crysdot
1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile 97%
250mg
$ 192.00

Alichem
1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile
1g
$ 518.40

Total 1 raw suppliers

Chemical Property of 2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)- (9CI)

Chemical Property:

Boiling Point:363.1±37.0 °C(Predicted)
PKA:-4.65±0.40(Predicted)
PSA：44.10000
Density:1.27±0.1 g/cm3(Predicted)
LogP:0.67768

Purity/Quality:: 1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)- (9CI)

There total 4 articles about 2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 20266-00-6
chloroacetic acid pyrrolidide

: 19158-51-1
P-toluenesulfonyl cyanide

: 274901-37-0
1-chloroacetyl-2-(S)-cyanopyrrolidine

Guidance literature:: With [Ir(2-(2,4-difluorophenyl)-4-(trifluoromethyl)pyridine)₂(5,5'-bis(trifluoromethyl)-2,2'-bipyridine)]PF₆; (S)-1,1'-binaphthyl-2,2'-diyl hydrogen phosphate; potassium carbonate; In dichloromethane; at 20 ℃; for 4h; Inert atmosphere; Sealed tube; Irradiation;
DOI:10.1002/chem.201801746

Reference yield: 42.0%

: 172876-96-9
3-oxo-1λ³-benzo[d][1,2]iodaoxole-1(3H)-carbonitrile

: 23500-10-9
(S)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid

: 274901-37-0
1-chloroacetyl-2-(S)-cyanopyrrolidine

Guidance literature:: With [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; Potassium benzoate; at 20 ℃; Molecular sieve; Irradiation;
DOI:10.1039/c6sc04907a