2-(3-BROMOPHENYL)ACETOPHENONE

Base Information

• Chemical Name: 2-(3-BROMOPHENYL)ACETOPHENONE
• CAS No.: 27798-44-3
• Molecular Formula: C14H11BrO
• Molecular Weight: 275.145
• Hs Code.: 2914700090
• Mol file: 27798-44-3.mol

Synonyms:2-(3-bromo-phenyl)-1-phenylethanone;Ethanone,2-(3-bromophenyl)-1-phenyl;2-(3-Bromophenyl)Acetophenone;m-Bromdesoxybenzoin;2-(2,4-DIFLUOROPHENOXY)-5-FLUORO-N-METHYLBENZYLAMINE;

Chemical Property of 2-(3-BROMOPHENYL)ACETOPHENONE

Chemical Property:

• Vapor Pressure: 7.49E-06mmHg at 25°C
• Boiling Point: 376oC at 760 mmHg
• Flash Point: 79.4oC
• PSA: 17.07000
• Density: 1.39g/cm3
• LogP: 3.87450

Purity/Quality:

99.90% ^*data from raw suppliers

2-(3-Bromophenyl)acetophenone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(3-BROMOPHENYL)ACETOPHENONE

There total 10 articles about 2-(3-BROMOPHENYL)ACETOPHENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

1-azidostyrene (16717-64-9) + 3-bromophenylhydrazine (40887-80-7) → 2-(3-bromophenyl)-1-phenylethan-1-one (27798-44-3)

Guidance literature:

With water; dihydrogen peroxide; at 25 ℃; Green chemistry;

DOI:10.1039/d1ob02023d

Reference yield: 82.0%

2-(3-bromo-benzylsulfanyl)-2'-iodo-biphenyl (880647-91-6) + benzoyl chloride (98-88-4) → 2-(3-bromophenyl)-1-phenylethan-1-one (27798-44-3)

Guidance literature:

Multistep reaction;

DOI:10.1002/anie.200501882

Reference yield: 77.0%

2-(3-bromophenyl)acetyl chloride (98288-51-8) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 2-(3-bromophenyl)-1-phenylethan-1-one (27798-44-3)

Guidance literature:

With aluminum (III) chloride; In dichloromethane; at 0 - 20 ℃;

DOI:10.1016/j.tetlet.2015.02.019

upstream raw materials:

2-(3-bromophenyl)acetyl chloride

benzene

2-(3-bromo-benzylsulfanyl)-2'-iodo-biphenyl

benzoyl chloride

Downstream raw materials:

3-(3-bromo-phenyl)-2-phenyl-1H-indole

3'-(2-oxo-2-phenyl-ethyl)-biphenyl-4-carboxylic acid ethyl ester

3'-(2-phenyl-1H-indol-3-yl)-biphenyl-4-carboxylic acid ethyl ester

3'-(2-phenyl-1H-indol-3-yl)-biphenyl-3-carboxylic acid ethyl ester