Propanamide, 3-chloro-N-(2-nitrophenyl)-

Base Information

• Chemical Name: Propanamide, 3-chloro-N-(2-nitrophenyl)-
• CAS No.: 2790-97-8
• Molecular Formula: C9H9ClN2O3
• Molecular Weight: 228.635
• Mol file: 2790-97-8.mol

Synonyms:3-Chlor-propionsaeure-(2-nitro-anilid);2'-Nitro-3-chloropropionanilide;3-Chloro-N-(2-nitro-phenyl)-propionamide;

Chemical Property of Propanamide, 3-chloro-N-(2-nitrophenyl)-

Chemical Property:

• Melting Point: 85 °C
• Boiling Point: 435.6±30.0 °C(Predicted)
• PSA: 74.92000
• Density: 1.409±0.06 g/cm3(Predicted)
• LogP: 2.75840

Purity/Quality:

99% ^*data from raw suppliers

3-Chloro-N-(2-nitrophenyl)propanamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Propanamide, 3-chloro-N-(2-nitrophenyl)-

There total 3 articles about Propanamide, 3-chloro-N-(2-nitrophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

2-nitro-aniline (88-74-4) + 2-chloropropionyl chloride (625-36-5) → 3-chloro-propionic acid-(2-nitro-anilide) (2790-97-8)

Guidance literature:

With acetic acid; at 0 - 20 ℃; for 1.5h;

DOI:10.1016/S0014-827X(01)01197-1

Reference yield:

3-chloropropanoyl bromide + 2-nitro-aniline (88-74-4) → 3-chloro-propionic acid-(2-nitro-anilide) (2790-97-8)

Guidance literature:

With benzene;

Reference yield:

→ 3-chloro-propionic acid-(2-nitro-anilide) (2790-97-8)

Guidance literature:

Amin I, ClCH2CH2COCl;

upstream raw materials:

2-nitro-aniline

2-chloropropionyl chloride

Downstream raw materials:

N-(2-(2,5-dichloropyrimidin-4-ylamino)phenyl)acrylamide