5-(2-Methoxyphenyl)-1,3,4-thiadiazol-2-amine

Base Information

Chemical Name:5-(2-Methoxyphenyl)-1,3,4-thiadiazol-2-amine
CAS No.:28004-56-0
Molecular Formula:C9H9N3OS
Molecular Weight:207.256
Hs Code.:2934999090
DSSTox Substance ID:DTXSID70353696
Wikidata:Q82131414
ChEMBL ID:CHEMBL1447599
Mol file:28004-56-0.mol

Synonyms:28004-56-0;5-(2-methoxyphenyl)-1,3,4-thiadiazol-2-amine;2-AMINO-5-(2-METHOXYPHENYL)-1,3,4-THIADIAZOLE;1,3,4-Thiadiazol-2-amine, 5-(2-methoxyphenyl)-;MFCD00981010;5-(2-Methoxy-phenyl)-[1,3,4]thiadiazol-2-ylamine;CBMicro_023243;Oprea1_344582;Oprea1_720385;RIBOSTAMYCINSULFATESALT;MLS000856231;CHEMBL1447599;SCHEMBL11335857;DTXSID70353696;HMS2686D04;CCG-10447;STK385478;AKOS000225674;AS-43479;SMR000286676;SY014177;BIM-0023087.P001;BB 0241868;CS-0214664;EU-0035044;FT-0768497;5-o-methoxyphenyl-2-amino-1,3,4-thiadiazole;EN300-186486;1,3,4-thiadiazol-2-amine,5-(2-methoxyphenyl)-;5-(2-methoxyphenyl)-1,3,4-thiadiazol-2-ylamine;AM-900/25025024;SR-01000402369;SR-01000402369-1;BRD-K20522925-001-07-1;F0346-1303;F1386-0071;Z332385270;5-(2-Methoxyphenyl)-1,3,4-thiadiazol-2-amine, AldrichCPR

Suppliers and Price of 5-(2-Methoxyphenyl)-1,3,4-thiadiazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(2-Methoxyphenyl)-1,3,4-thiadiazol-2-amine
500mg
$ 200.00

Matrix Scientific
2-Amino-5-(2-methoxyphenyl)-1,3,4-thiadiazole
1g
$ 229.00

Crysdot
5-(2-Methoxyphenyl)-1,3,4-thiadiazol-2-amine 95+%
250mg
$ 100.00

Crysdot
5-(2-Methoxyphenyl)-1,3,4-thiadiazol-2-amine 95+%
5g
$ 552.00

Crysdot
5-(2-Methoxyphenyl)-1,3,4-thiadiazol-2-amine 95+%
1g
$ 251.00

American Custom Chemicals Corporation
5-(2-METHOXYPHENYL)-1,3,4-THIADIAZOL-2-AMINE 95.00%
10G
$ 1905.75

American Custom Chemicals Corporation
5-(2-METHOXYPHENYL)-1,3,4-THIADIAZOL-2-AMINE 95.00%
5G
$ 1316.70

American Custom Chemicals Corporation
5-(2-METHOXYPHENYL)-1,3,4-THIADIAZOL-2-AMINE 95.00%
1G
$ 866.25

Alichem
5-(2-Methoxyphenyl)-1,3,4-thiadiazol-2-amine
10g
$ 840.84

Alichem
5-(2-Methoxyphenyl)-1,3,4-thiadiazol-2-amine
5g
$ 560.56

Total 9 raw suppliers

Chemical Property of 5-(2-Methoxyphenyl)-1,3,4-thiadiazol-2-amine

Chemical Property:

Boiling Point:404.7±47.0 °C(Predicted)
PKA:2.95±0.10(Predicted)
PSA：89.27000
Density:1.320±0.06 g/cm3(Predicted)
LogP:2.37710
Storage Temp.:2-8°C(protect from light)
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:207.04663309
Heavy Atom Count:14
Complexity:193

Purity/Quality:

97% ^*data from raw suppliers

5-(2-Methoxyphenyl)-1,3,4-thiadiazol-2-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1C2=NN=C(S2)N

Technology Process of 5-(2-Methoxyphenyl)-1,3,4-thiadiazol-2-amine

There total 5 articles about 5-(2-Methoxyphenyl)-1,3,4-thiadiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 2290-65-5
trimethylsilyl isothiocyanate

: 7466-54-8
2-methoxybenzoylhydrazine

: 28004-56-0
2-amino-5-(o-methoxyphenyl)-1,3,4-thiadiazole

Guidance literature:: trimethylsilyl isothiocyanate; 2-methoxybenzoylhydrazine; In ethanol; Reflux;

With sulfuric acid; In ethanol; at 20 ℃;
DOI:10.1039/c3ra00159h

Reference yield: 49.2%

: 28004-56-0
2-amino-5-(o-methoxyphenyl)-1,3,4-thiadiazole

Guidance literature:: With trifluoroacetic acid; at 70 ℃; for 8h;

Reference yield: 43.0%

: 79-19-6
thiosemicarbazide

: 579-75-9
2-Methoxybenzoic acid

: 28004-56-0
2-amino-5-(o-methoxyphenyl)-1,3,4-thiadiazole

Guidance literature:: 2-Methoxybenzoic acid; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃;

thiosemicarbazide; With trichlorophosphate; In dichloromethane; N,N-dimethyl-formamide; at 90 ℃; for 1h;