methyl 2-O-benzyl-4,6-O-benzylidene-3-O-(3,6-dideoxy-2,4-di-O-p-nitrobenzoyl-α-D-xylo-hexopyranosyl)-α-D-mannopyranoside

Base Information

• Chemical Name: methyl 2-O-benzyl-4,6-O-benzylidene-3-O-(3,6-dideoxy-2,4-di-O-p-nitrobenzoyl-α-D-xylo-hexopyranosyl)-α-D-mannopyranoside
• CAS No.: 59892-64-7
• Molecular Formula: C₄₁H₄₀N₂O₁₅
• Molecular Weight: 800.773
• Mol file: 59892-64-7.mol

Synonyms:

Chemical Property of methyl 2-O-benzyl-4,6-O-benzylidene-3-O-(3,6-dideoxy-2,4-di-O-p-nitrobenzoyl-α-D-xylo-hexopyranosyl)-α-D-mannopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-O-benzyl-4,6-O-benzylidene-3-O-(3,6-dideoxy-2,4-di-O-p-nitrobenzoyl-α-D-xylo-hexopyranosyl)-α-D-mannopyranoside

There total 3 articles about methyl 2-O-benzyl-4,6-O-benzylidene-3-O-(3,6-dideoxy-2,4-di-O-p-nitrobenzoyl-α-D-xylo-hexopyranosyl)-α-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitro-benzoyl chloride (122-04-3) → methyl 2-O-benzyl-4,6-O-benzylidene-3-O-(3,6-dideoxy-2,4-di-O-p-nitrobenzoyl-α-D-xylo-hexopyranosyl)-α-D-mannopyranoside (59892-64-7)

Guidance literature:

Multi-step reaction with 2 steps

2: 1.) mercury cyanide, molecular sieves / 1.) toluene, nitromethane, 20 deg C, 16 h, 2.) toluene, 20 deg C, 40 h

With molecular sieve; mercury(II) cyanide;

Reference yield:

3-hydroxy-5-(1-hydroxyethyl)dihydrofuran-2-one (79645-45-7) → methyl 2-O-benzyl-4,6-O-benzylidene-3-O-(3,6-dideoxy-2,4-di-O-p-nitrobenzoyl-α-D-xylo-hexopyranosyl)-α-D-mannopyranoside (59892-64-7)

Guidance literature:

Multi-step reaction with 2 steps

2: 1.) mercury cyanide, molecular sieves / 1.) toluene, nitromethane, 20 deg C, 16 h, 2.) toluene, 20 deg C, 40 h

With molecular sieve; mercury(II) cyanide;

Reference yield:

3,6-dideoxy-2,4-di-O-(p-nitrobenzoyl)-α-D-xylo-hexopyranosyl bromide (59892-66-9) + methyl 2-O-benzyl-4,6-O-benzylidene-α-D-mannopyranoside (23392-29-2) → methyl 2-O-benzyl-4,6-O-benzylidene-3-O-(3,6-dideoxy-2,4-di-O-p-nitrobenzoyl-β-D-xylo-hexopyranosyl)-α-D-mannopyranoside + methyl 2-O-benzyl-4,6-O-benzylidene-3-O-(3,6-dideoxy-2,4-di-O-p-nitrobenzoyl-α-D-xylo-hexopyranosyl)-α-D-mannopyranoside (59892-64-7)

Guidance literature:

With molecular sieve; mercury(II) cyanide; Yield given. Multistep reaction. Yields of byproduct given; 1.) toluene, nitromethane, 20 deg C, 16 h, 2.) toluene, 20 deg C, 40 h;

upstream raw materials:

3,6-dideoxy-2,4-di-O-(p-nitrobenzoyl)-α-D-xylo-hexopyranosyl bromide

methyl 2-O-benzyl-4,6-O-benzylidene-α-D-mannopyranoside

4-nitro-benzoyl chloride

3-hydroxy-5-(1-hydroxyethyl)dihydrofuran-2-one