Benzene, 4-nitro-1,2-bis(phenylmethoxy)-

Base Information

• Chemical Name: Benzene, 4-nitro-1,2-bis(phenylmethoxy)-
• CAS No.: 28387-13-5
• Molecular Formula: C20H17NO4
• Molecular Weight: 335.359
• Mol file: 28387-13-5.mol

Synonyms:3,4-dibenzyloxy-1-nitrobenzene;4-Nitro-brenzcatechin-dibenzylaether;3,4-Bis(phenylmethoxy)nitrobenzene;4-Nitro-1.2-dibenzyloxy-benzol;1,2-Bis-benzyloxy-4-nitro-benzol;3,4-bis-benzyloxy-nitrobenzene;

Chemical Property of Benzene, 4-nitro-1,2-bis(phenylmethoxy)-

Chemical Property:

• Melting Point: 97 °C
• Boiling Point: 512.1±40.0 °C(Predicted)
• PSA: 64.28000
• Density: 1.238±0.06 g/cm3(Predicted)
• LogP: 5.27600

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzene, 4-nitro-1,2-bis(phenylmethoxy)-

There total 9 articles about Benzene, 4-nitro-1,2-bis(phenylmethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1,2-dihydroxy-4-nitrobenzene (3316-09-4) + benzyl bromide (100-39-0) → 1,2-bis(benzyloxy)-4-nitrobenzene (28387-13-5)

Guidance literature:

In acetone; at 60 ℃;

Reference yield:

3,4-difluoronitrobenzene (369-34-6) + benzyl alcohol (100-51-6,185532-71-2) → 1-(benzyloxy)-2-fluoro-4-nitrobenzene (76243-24-8) + 1,2-bis(benzyloxy)-4-nitrobenzene (28387-13-5)

Guidance literature:

benzyl alcohol; With sodium hydride; In ISOPROPYLAMIDE; at 20 ℃; for 1h;

3,4-difluoronitrobenzene; In ISOPROPYLAMIDE; at 0 ℃; for 1h;

Reference yield:

1,2-dihydroxy-4-nitrobenzene (3316-09-4) → 1,2-bis(benzyloxy)-4-nitrobenzene (28387-13-5)

Guidance literature:

Multi-step reaction with 2 steps

1: NaH / dimethylformamide / Ambient temperature

2: NaH / dimethylformamide

With sodium hydride; In N,N-dimethyl-formamide;

DOI:10.1016/S0960-894X(97)00124-8

upstream raw materials:

1,2-di(benzyloxy)benzene

1,2-dihydroxy-4-nitrobenzene

benzyl chloride

2-benzyloxy-5-nitrophenol

Downstream raw materials:

1,2-dihydroxy-4-nitrobenzene

3,4-Bis(phenylmethoxy)benzeneamine

4-nitro-1,2-benzenediol diacetate

(3,4-Bis-benzyloxy-phenyl)-thiourea