107963-01-9 Usage
Description
N-(3,4-DIMETHOXYPHENYL)THIOACETAMIDE is a thioacetamide derivative with the molecular formula C11H15NO3S. It features a sulfur atom attached to an acetamide group and a 3,4-dimethoxyphenyl group, which may confer potential biological activity. Related compounds with similar structures have been found to possess anti-inflammatory, antioxidant, and neuroprotective properties. Thioacetamide derivatives are utilized in various synthetic and pharmaceutical applications due to their diverse reactivity and functionality. However, the specific properties and uses of N-(3,4-DIMETHOXYPHENYL)THIOACETAMIDE require further investigation to determine its individual chemical and physical characteristics.
Uses
Used in Pharmaceutical Industry:
N-(3,4-DIMETHOXYPHENYL)THIOACETAMIDE is used as a potential pharmaceutical candidate for its possible biological activity, which may include anti-inflammatory, antioxidant, and neuroprotective properties. Its specific applications and efficacy would need to be determined through further research and development.
Used in Chemical Synthesis:
N-(3,4-DIMETHOXYPHENYL)THIOACETAMIDE is used as a chemical intermediate in the synthesis of various compounds due to its thioacetamide functionality and the presence of the 3,4-dimethoxyphenyl group, which can be further modified or reacted to produce desired products.
Check Digit Verification of cas no
The CAS Registry Mumber 107963-01-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,7,9,6 and 3 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 107963-01:
(8*1)+(7*0)+(6*7)+(5*9)+(4*6)+(3*3)+(2*0)+(1*1)=129
129 % 10 = 9
So 107963-01-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H13NO2S/c1-7(14)11-8-4-5-9(12-2)10(6-8)13-3/h4-6H,1-3H3,(H,11,14)
107963-01-9Relevant articles and documents
Iron-Catalyzed Regioselective Synthesis of 2-Arylbenzoxazoles and 2-Arylbenzothiazoles via Alternative Reaction Pathways
Henry, Martyn C.,Abbinante, Vincenzo Mirco,Sutherland, Andrew
supporting information, p. 2819 - 2826 (2020/04/10)
A one-pot regioselective method for the preparation of 2-arylbenzoxazoles from N-arylbenzamides has been developed using iron(III)-catalyzed bromination of the aryl ring, followed by copper(I)-catalyzed O-cyclization with the benzamide side chain. In contrast, reaction of N-arylthiobenzamides with N-bromosuccinimide and iron triflimide led directly to the isolation of the corresponding 2-arylbenzothiazoles via intramolecular C–S bond formation. Mechanistic and control experiments suggest that in this case, bromination occurs at the sulfur atom, resulting in a reactive intermediate that can undergo electrophilic aromatic substitution and S-cyclization. The scope of both processes was explored yielding a range of structural analogues, including a pharmaceutically active compound for the treatment of Duchenne muscular dystrophy and an affinity agent of the amyloid-beta protein in Alzheimer's disease.
