62306-04-1

Usage

Uses

Used in Pharmaceutical Synthesis:
5,6-Dimethoxy-2-methyl-benzothiazole is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs and medications.
Used in Agrochemical Synthesis:
In the agrochemical industry, 5,6-Dimethoxy-2-methyl-benzothiazole is utilized as a precursor in the production of agrochemicals, potentially enhancing crop protection and yield.
Used as an Antimicrobial Agent:
5,6-Dimethoxy-2-methyl-benzothiazole is used as an antimicrobial agent for its potential to treat various infections, offering a new avenue for combating microbial threats.
Used in Anti-inflammatory Applications:
5,6-DIMETHOXY-2-METHYL-BENZOTHIAZOLE is employed as an anti-inflammatory agent, leveraging its properties to potentially alleviate inflammation and associated conditions.
Used in Antiviral Applications:
5,6-Dimethoxy-2-methyl-benzothiazole is used as an antiviral agent, being studied for its potential to inhibit viral replication and treat viral infections.

InChI:InChI=1/C10H11NO2S/c1-6-11-7-4-8(12-2)9(13-3)5-10(7)14-6/h4-5H,1-3H3

Upstream product

• 58249-73-3 bis-(4,5-dimethoxy-2-nitro-phenyl)-disulfane 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 
• 6315-89-5 3,4-dimethoxyaniline 
• 881-70-9 3',4'-dimethoxyacetanilide 
• 107963-01-9 N-(3,4-dimethoxyphenyl)thioacetamide 
• 51072-66-3 1-bromo-4,5-dimethoxy-2-nitro-benzene 

Downstream Products

• 102749-55-3 3-ethyl-2-[bis-(4-nitro-phenylazo)-methylene]-5,6-dimethoxy-2,3-dihydro-benzothiazole 
• 68252-56-2 2-methyl-5,6-dihydroxybenzothiazole 
• 1565798-01-7 5,6-dimethoxy-2-((1E,3E)-4-(4-nitrophenyl)buta-1,3-dienyl)benz[d]thiazole 
• 1565797-08-1 N-(4-((1E,3E)-4-(5,6-dimethoxybenzo[d]thiazole-2-yl)buta-1,3-dienyl)phenyl)acetamide 
• 1565798-02-8 4-((1E,3E)-4-(5,6-dimethoxybenzo[d]thiazole-2-yl)buta-1,3-dienyl)aniline 
• 1565797-09-2 3-(4-((1E,3E)-4-(5,6-dimethoxybenzo[d]thiazole-2-yl)buta-1,3-dienyl)phenylamino)propan-1-ol 
• 1565797-10-5 4-((1E,3E)-4-(5,6-dimethoxybenzo[d]thiazole-2-yl)buta-1,3-dienyl)-N-isopropylaniline 

Relevant academic research and scientific papers

Iron-Catalyzed Regioselective Synthesis of 2-Arylbenzoxazoles and 2-Arylbenzothiazoles via Alternative Reaction Pathways

A one-pot regioselective method for the preparation of 2-arylbenzoxazoles from N-arylbenzamides has been developed using iron(III)-catalyzed bromination of the aryl ring, followed by copper(I)-catalyzed O-cyclization with the benzamide side chain. In contrast, reaction of N-arylthiobenzamides with N-bromosuccinimide and iron triflimide led directly to the isolation of the corresponding 2-arylbenzothiazoles via intramolecular C–S bond formation. Mechanistic and control experiments suggest that in this case, bromination occurs at the sulfur atom, resulting in a reactive intermediate that can undergo electrophilic aromatic substitution and S-cyclization. The scope of both processes was explored yielding a range of structural analogues, including a pharmaceutically active compound for the treatment of Duchenne muscular dystrophy and an affinity agent of the amyloid-beta protein in Alzheimer's disease.

NEW PHARMACEUTICAL COMPOUNDS

Compounds of formula (I), wherein R1-R4, X, Y and Z are as defined in claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors.

Crown-containing spironaphthoxazines and spiropyrans 3. Synthesis and investigation of the merocyanine form of crown-containing spirobenzothiazolinonaphthoxazine

A method for the synthesis of the spirobenzothiazolinonaphthoxazine, stable in the merocyanine form and containing a crown-ether fragment was developed. The complexing properties of the prepared merocyanine compound and the spectroscopic and photochromic characteristics of its complexes with alkaline earth metal cations were studied by NMR and UV spectroscopy. The results were analyzed using quantum-chemical calculations. The addition of alkaline earth metal perchlorates to a solution of a crown ether-containing merocyanine dye in MeCN results in the coordination of metal cations to two binding centers, namely, the crown-ether fragment and the merocyanine oxygen atom. This gives rise to two types of complexes, which differ substantially in their structurally. The complexation induces changes in the UV spectra and influences on the photochromic behavior of the prepared compound.

Benzazole compounds and their use

The present invention discloses a method for repelling insects, mites and ticks from warm-blooded animals with a benzazole compound.