112283-40-6Relevant articles and documents
Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles
Hamed, Refaat B.,Mecinovic, Jasmin,Ducho, Christian,Claridge, Timothy D. W.,Schofield, Christopher J.
, p. 1413 - 1415 (2010)
The utility of wild-type and variant carboxymethylproline synthases for biocatalysis was demonstrated by preparing functionalised 5-, 6- and 7-membered N-heterocycles from amino acid aldehydes and (alkylated) malonyl-coenzyme A derivatives; the N-heterocycles produced were converted to the corresponding bicyclic β-lactams by a carbapenem synthetase. The Royal Society of Chemistry 2010.
Three unusual reactions mediate carbapenem and carbapenam biosynthesis [1]
Li, Rongfeng,Stapon, Anthony,Blanchfield, Joanne T.,Townsend, Craig A.
, p. 9296 - 9297 (2000)
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