114967-89-4Relevant articles and documents
SYNTHESIS AND PROPERTIES OF ESTERS OF 21-THIOALKANOIC ACIDS OF CORTICOSTEROIDS
Pshenichnyi, V. N.,Mikhal'chuk, A. L.,Borisov, E. V.,Khripach, V. A.
, p. 890 - 895 (2007/10/02)
The esters of the 21-thioalkanoic acids of corticosteroids were synthesized by the reaction of the 21-sulfonic esters and 21-halogen derivatives of corticosteroids with methyl mercaptoacetate in the presence of bases or by heating in aprotic dipolar solvents and also from the 21-thioalkanoic acids and alcohols by means of carbodiimides.The esters are hydrolyzed to the 21-thioalkanoic acids and are also oxidized to sulfoxides.
SYNTHESIS AND ANTI-INFLAMMATORY ACTIVITY OF 21-THIO DERIVATIVES OF CORTICOSTEROIDS
Pshenitskii, V. N.,Mikhalchuk, A. L.,Khripach, V. A.,Kuz'mitskii, B. V.,Mzulo, N. A.,Shafranskaya, G. A.
, p. 225 - 229 (2007/10/02)
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