118645-86-6Relevant articles and documents
NEW ONE-POT SYNTHESIS OF ENAMINEDINITRILES
Berry, Robert W. H.,Drewry, Peter C.,Hodson, Harold F.
, p. 958 - 975 (2007/10/02)
A convenient procedure is reported for the one-pot preparation of enaminedinitriles.This involves the sodium methoxide-catalysed addition of methanol to a suitably substituted nitrile followed by reaction of the resulting imidate with malononitrile.The mechanism, scope and limitations of the synthesis have been investigated.Spectroscopic evidence is presented that the products exist in the enaminedinitrile rather than in the tautomeric imino form.Various reactions of the compounds including halogen exchange, anion formation and amine displacement have been studied and used to extend the range of enaminedinitriles prepared.