118663-74-4Relevant articles and documents
Acetylation of secondary hydroxy groups of α- and β-cyclodextrines silyl derivatives
Grachev,Edunov,Kurochkina,Levina,Nifant'ev
, p. 322 - 329 (2011)
The application of acetyl chloride in the combination with different solvents and bases permitted the preparation of silyl derivatives of α- and β-cyclodextrines containing a definite amount of acetyl substituents on the secondary hydroxy groups. It was found that by means of the 1H and 13C NMR spectroscopy it is possible to make an exact attribution of acetyl groups to C2 or C3 carbon atoms of carbohydrate fragments of α- and β-cyclodextrines. Desilylation with ammonium fluoride in methanol gives acetyl derivatives of cyclodextrines containing free primary hydroxy groups.
