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120570-09-4

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  • SAGECHEM/(3R)?-N-?[(1S)?-?1-?phenylethyl]?-1-?Azabicyclo[2.2.2]?octan-?3-?amine hydrochloride/SAGECHEM/Manufacturer in China

    Cas No: 120570-09-4

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  • (+)-N-(1(S)-Phenylethyl)-1-azabicyclo[2.2.2]octan-3(R)-amine dihydrochloride, 98%

    Cas No: 120570-09-4

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120570-09-4 Usage

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(3R)-N-[(1S)-1-Phenylethyl]-1-azabicyclo[2.2.2]octan-3-amine Dihydrochloride is the derivative of 3-Quinuclidinone Hydrochloride (Q795795), which is used in the synthesis of cevimeline, a thiolating agent. Also used in the preparation of novel CB1 and CB2 cannabinoid receptor ligands.

Check Digit Verification of cas no

The CAS Registry Mumber 120570-09-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,5,7 and 0 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 120570-09:
(8*1)+(7*2)+(6*0)+(5*5)+(4*7)+(3*0)+(2*0)+(1*9)=84
84 % 10 = 4
So 120570-09-4 is a valid CAS Registry Number.
InChI:InChI=1/C15H22N2.2ClH/c1-12(13-5-3-2-4-6-13)16-15-11-17-9-7-14(15)8-10-17;;/h2-6,12,14-16H,7-11H2,1H3;2*1H/t12-,15-;;/m0../s1

120570-09-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (3R)-N-[(1S)-1-Phenylethyl]quinuclidin-3-amine dihydrochloride

1.2 Other means of identification

Product number -
Other names (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:120570-09-4 SDS

120570-09-4Relevant articles and documents

Improved preparation of (R) and (S)-3-aminoquinuclidine dihydrochloride

Kowalczyk, Bruce A.,Rohloff, John C.,Dvorak, Charles A.,Gardner, John O.

, p. 2009 - 2015 (2007/10/03)

An improved procedure for the synthesis of either (R) or (S)-3-aminoquinuclidine was developed. Key intermediate imine 2 was made in a one pot process using lithium oxide as the base and molecular sieves.

Enantiomers of absolute configuration S of amide derivatives of 3-aminoquinuclidine, the process for preparing them and their application in therapy

-

, (2008/06/13)

Enantiomer of absolute configuration S of formula: STR1 where: X=O or S; and Ar denotes a: * phenyl ring substituted with one, two or three C1 -C4 alkoxy groups; * phenyl ring substituted at the 2-position with a OCH3 group and at the 5-position with a halogen atom or a lower alkylcarbonyl group; * phenyl ring substituted at the 2-position with OCH3, at the 4-position with NH2 or alkylcarbonyl-NH and at the 5-position with a halogen; * 3-fluoro-2-methoxyphenyl group; * 5-pyrimidinyl group substituted at the 2-position with NH2 and in the 4-position with alkoxy or phenyloxy. These compounds are useful as medicinal products having activity in respect of gastric movements and antiemetic activity.

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