124946-65-2

• 

• Basic information

  1. Product Name: 3-Buten-2-one, 4-(2-hydroxy-4-methoxyphenyl)-
  2. Synonyms:
  3. CAS NO:124946-65-2
  4. Molecular Formula: C11H12O3
  5. Molecular Weight: 192.214
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 124946-65-2.mol
  9. Article Data: 2

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: N/A
  5. Density: N/A
  6. Refractive Index: N/A
  7. Storage Temp.: N/A
  8. Solubility: N/A
  9. CAS DataBase Reference: 3-Buten-2-one, 4-(2-hydroxy-4-methoxyphenyl)-(CAS DataBase Reference)
  10. NIST Chemistry Reference: 3-Buten-2-one, 4-(2-hydroxy-4-methoxyphenyl)-(124946-65-2)
  11. EPA Substance Registry System: 3-Buten-2-one, 4-(2-hydroxy-4-methoxyphenyl)-(124946-65-2)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 124946-65-2(Hazardous Substances Data)

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124946-65-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 124946-65-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,9,4 and 6 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 124946-65:
(8*1)+(7*2)+(6*4)+(5*9)+(4*4)+(3*6)+(2*6)+(1*5)=142
142 % 10 = 2
So 124946-65-2 is a valid CAS Registry Number.

124946-65-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name	4-(2-hydroxy-4-methoxyphenyl)but-3-en-2-one

1.2 Other means of identification

Product number	-
Other names	4-(2-Hydroxy-4-methoxy-phenyl)-but-3-en-2-on

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:124946-65-2 SDS

124946-65-2Upstream product

• 673-22-3 2-Hydroxy-4-methoxybenzaldehyde 
• 67-64-1 acetone 

124946-65-2Downstream Products

124946-65-2Relevant articles and documents

Anti-tumor agents 255: Novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents

Tatsuzaki, Jin,Taniguchi, Masahiko,Bastow, Kenneth F.,Nakagawa-Goto, Kyoko,Morris-Natschke, Susan L.,Itokawa, Hideji,Baba, Kimiye,Lee, Kuo-Hsiung

, p. 6193 - 6199 (2008/03/27)

Esterification of glycyrrhetinic acid (GA) with dehydrozingerone (DZ) resulted in a novel cytotoxic GA-DZ conjugate. Based on this exciting finding, we conjugated eleven different DZ analogs with GA or other triterpenoids, including oleanoic acid (OA) or ursolic acid (UA). In an in vitro anti-cancer assay using nine different human tumor cell lines, most of the GA-DZ conjugates showed significant potency. Particularly, compounds 5, 29, and 30 showed significant cytotoxic effects against LN-Cap, 1A9, and KB cells with ED50 values of 0.6, 0.8, and 0.9 μM, respectively. Similar conjugates between DZ and OA or UA were inactive suggesting that the GA component is critical for activity. Notably, although GA-DZ conjugates showed potent cytotoxic activity, the individual components (GA and DZ analogs) were inactive. Thus, GA-DZ conjugates are new chemical entities and represent interesting hits for anti-cancer drug discovery and development.

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