129482-56-0 Usage
Description
4,5-Dichloro-4,5-dimethyl-1,3-dioxolan-2-one is a colorless liquid chemical compound with a strong odor, known for its use as a solvent and as an intermediate in the production of pharmaceuticals and other organic compounds. It is highly flammable and also used in the synthesis of various biologically active compounds. Despite its low acute toxicity, it can cause irritation to the skin, eyes, and respiratory system upon exposure, necessitating proper handling and safety precautions.
Uses
Used in Pharmaceutical Industry:
4,5-Dichloro-4,5-dimethyl-1,3-dioxolan-2-one is used as a solvent and intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and improving the manufacturing process of existing ones.
Used in Organic Compounds Production:
In the chemical industry, 4,5-Dichloro-4,5-dimethyl-1,3-dioxolan-2-one serves as a key intermediate in the production of other organic compounds, facilitating the creation of a wide range of chemical products.
Used in Synthesis of Biologically Active Compounds:
4,5-Dichloro-4,5-dimethyl-1,3-dioxolan-2-one is utilized in the synthesis of biologically active compounds, playing a crucial role in the development of new therapeutic agents and enhancing the effectiveness of existing treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 129482-56-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,4,8 and 2 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 129482-56:
(8*1)+(7*2)+(6*9)+(5*4)+(4*8)+(3*2)+(2*5)+(1*6)=150
150 % 10 = 0
So 129482-56-0 is a valid CAS Registry Number.
129482-56-0Relevant articles and documents
A Convenient and Practical Preparation of 4-Chloromethyl-5-methyl-1,3-dioxol-2-one
Ikeda, Shoji,Takebe, Yasushi,Hirayama, Ryoichi,Sakamoto, Fumio,Iuchi, Koji,Tsukamoto, Goro
, p. 394 - 397 (2007/10/02)
A new synthetic method for 4-chloromethyl-5-methyl-1,3-dioxol-2-one (1c), which is useful for preparing prodrugs, has been developed.Ene-chlorination of 4,5-dimethyl-1,3-dioxol-2-one (2) with chlorine or sulfuryl chloride afforded 4-chloro-4-methyl-5-methylene-1,3-dioxolan-2-one (3) in good yield.Compound 3 underwent allylic rearrangement to afford 1c quantitatively.The overall yield of 1c from 2 was approximately 80percent. Keywords---4-chloromethyl-5-methyl-1,3-dioxol-2-one; 4,5-dimethyl-1,3-dioxol-2-one; 4-chloro-4-methyl-5-methylene-1,3-dioxolan-2-one; ene-chlorination; allylic rearrangement; (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl group; promoiety; prodrug