132605-23-3Relevant articles and documents
SUBSTITUED 3,4-DIHYDROTHIENO [2,3-D] PYRMIDINES AS TISSUE TRANSGLUTAMINASE INHIBITORS
-
Page/Page column 57; 58, (2010/11/08)
The present invention provides novel compounds and methods useful for treating transglutaminase associated disorders such as celiac spru, Alzheimer's disease and Huntington's disease. Certain compounds of the invention are tissue transglutaminase inhibito
Synthesis and pharmacological activities of some 3-substituted thienopyrimidin-4-one-2-thiones
Cannito, A.,Perrissin, M.,Luu-Duc, C.,Huguet, F.,Gaultier, C.,Narcisse, G.
, p. 635 - 639 (2007/10/02)
The condensation of substituted 2-amino-3-carbethoxy-thiophenes with methyl, ethyl and phenyl isothiocyanate yields the corresponding thienylthioureas which cyclize in ethanol saturated with dry hydrochloric acid to form 3-substituted thienopyrimid