132682-98-5 Usage
Uses
Glufosfamide is an alkylating cytotoxic agent with increased antitumor selectivity and active transmembrane transport mechanism, that belongs to the oxazaphosphorine class. It is an attractive new agent for cancer therapy in humans.
Check Digit Verification of cas no
The CAS Registry Mumber 132682-98-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,6,8 and 2 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 132682-98:
(8*1)+(7*3)+(6*2)+(5*6)+(4*8)+(3*2)+(2*9)+(1*8)=135
135 % 10 = 5
So 132682-98-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H21Cl2N2O7P/c11-1-3-13-22(19,14-4-2-12)21-10-9(18)8(17)7(16)6(5-15)20-10/h6-10,15-18H,1-5H2,(H2,13,14,19)/t6-,7-,8+,9-,10+/m1/s1
132682-98-5Relevant articles and documents
GLYCOCONJUGATES OF PHOSPHORAMIDATE ALKYLATORS FOR TREATMENT OF CANCER
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Page/Page column 35, (2010/11/29)
Bromoglufosfamide and related compounds are useful in the treatment of cancer and other hyperproliferative diseases. Glufosfamide and bromoglufosfamide are synthesized by reacting the corresponding tetracetyl derivatives with MeOH and a catalytic amount of MeO(-). Tetraacetyl glufosfamide is obtained by reacting a tetraacetyl trichloroacetamidate intermediate of glucose, ifosfamide mustard, and an acid in an anhydrous polar solvent.