139021-82-2Relevant articles and documents
SYNTHESIS OF SMALL MOLECULES INSPIRED BY PHOMOXANTHONE A
-
Page/Page column 91-92, (2022/02/28)
Methods, compositions, and kits are provided for synthesizing bioactive chromane, the method including: constructing a tertiary ether stereocenter enantioselectively by catalyzed alkynylation of a substituted chromenone to obtain a chromanone; reducing alkyne and ketone in the chromanone to obtain a chroman; and converting ester to methyl group thereby obtaining chromane.
Asymmetric copper complex and cyclopropanation reaction using the same
-
, (2008/06/13)
There are disclosed asymmetric copper complex comprising, as components, (a) an optically active bisoxazoline compound of formula (1): wherein R1 and R2 are different and each represent a hydrogen atom, an alkyl group, a cycloalkyl group, or a phenyl or aralkyl group which may be substituted, R3 and R4 each represent a hydrogen atom, an alkyl group, a cycloalkyl group, or a phenyl or aralkyl group which may be substituted, or R3 and R4 may be bonded to each other to form a C3-5 cyclic alkylene group, R5 represents a hydrogen atom or a C1-6 alkyl group, or the two R5 groups may be bonded to each other to represent a C3-5 cyclic alkylene group, (b) a monovalent or divalent copper compound, and (c) a strong acid or a Lewis acid or a mixture thereof, and a process for producing an optically active cyclopropanecarboxylate using the same.