145414-65-9 Usage
Structure
Contains a pyrimidine ring and a dioxolane ring
Stereochemistry
(2S,4S) configuration
Functional groups
a. Hydroxymethyl group attached to the dioxolane ring
b. Two carbonyl groups (one in the pyrimidine ring and one in the dioxolane ring)
Substituents
a. Methyl group on the pyrimidine ring
b. Hydroxymethyl group on the dioxolane ring
Potential applications
a. Biological activities
b. Pharmaceutical research
c. Drug development
Further research
Studies may be necessary to determine specific properties and potential uses of the compound
Check Digit Verification of cas no
The CAS Registry Mumber 145414-65-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,4,1 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 145414-65:
(8*1)+(7*4)+(6*5)+(5*4)+(4*1)+(3*4)+(2*6)+(1*5)=119
119 % 10 = 9
So 145414-65-9 is a valid CAS Registry Number.
145414-65-9Relevant articles and documents
2-Substituted-4-substituted-1,3-dioxolanes and use thereof
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Page column 51 -52, (2010/11/29)
Nucleoside analogues containing a 1,3-dioxolane structure are suitable antiviral agents, particulary for the treatment of the HIV infections in mammals, especially humans. Examples of the nucleoside analogues include: cis-2-acetoxymethyl-4-(thymin-1′-yl)-1,3,-dioxolane, cis-2-hydroxymethyl-4-(thymin-1′-yl)-1,3-dioxolane, cis-2-benzoyloxymethyl-4-(cytosin-1′-yl)-1,3-dioxolane, and cis-2-hydroxymethyl-4-(cytosin-1′-yl)-1,3-dioxolane. These compounds can be in the form of their racemates or their separate enantiomers.
In situ complexation directs the stereochemistry of N-glycosylation in the synthesis of oxathiolanyl and dioxolanyl nucleoside analogues
Choi, Woo-Baeg,Wilson, Lawrence J.,Yeola, Suresh,Liotta, Dennis C.,Schinazi, Raymond F.
, p. 9377 - 9379 (2007/10/02)
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