145354-83-2Relevant academic research and scientific papers
L-β-(2S,4S)- and L-α-(2S,4R)-dioxolanyl nucleosides as potential anti- HIV agents: Asymmetric synthesis and structure-activity relationships
Kim,Schinazi,Shanmuganathan,Jeong,Beach,Nampalli,Cannon,Chu
, p. 519 - 528 (2007/10/02)
In order to study the structure-activity relationships of L-(2S,4S)- and L-(2S,4R)-dioxolanyl nucleosides as potential anti-HIV agents, various enantiomerically pure L-(2S,4S)- and (2S,4R)-dioxolanylpyrimidine and - purine nucleosides have been synthesize
Potent Anti-HIV and Anti-HBV Activities of (-)-L-&β-Dioxolane-C and (+)-L-&β-Dioxolane-T and Their Asymmetric Syntheses.
Kim, Hea O.,Shanmuganathan, Kirupathevy,Alves, Antonio J.,Jeong, Lak S.,Beach, J. Warren,et al.
, p. 6899 - 6902 (2007/10/02)
The asymmetric syntheses of (+)-L-β-dioxolane-T and (-)-L-β-dioxolane-C were accomplished starting from 1,6-anhydro-L-β-gulopyranose, and their anti-HIV and anti-HBV activities were evaluated in human PBM cells, CEM cells and 2.2.15 cells, respectively. K
