146288-30-4Relevant articles and documents
Convergent synthesis of tetra- and penta-saccharide fragments of dimeric Lewis X
Forman, Adam,Hendel, Jenifer,Auzanneau, France-Isabelle
, (2019)
The convergent synthesis of tetra- and penta-saccharide fragments of the TACA dimeric Lex is described. The synthetic strategy relied on the preparation of a protected GlcNTCA-(1,3)-Gal-(1,4)-GlcNAc trisaccharide diol free at O-3 of both glucos
Use of sodium iodide and crown ether in the synthesis of N-acetylglucosamine glycosides
Kur'yanov,Zemlyakov,Chupakhina,Chirva
, p. 282 - 283 (2007/10/03)
A pair of sodium iodide-crown ether reagents was used in the synthesis of N-acetylglucosamine glycosides. At room temperature, the reaction resulted in β-glycosides, whereas at 85-90°C, it gave a mixture of anomers or α-anomer only.
A spacer-modified disaccharide as a photoaffinity reagent for the acceptor-binding area of bovine (1->4)-β-D-galactosyltransferase: comparison of its acceptor properties with those of other 2-acetamido-2-deoxy-β-D-glucopyranosides
Ats, Sandor-Csaba,Lehmann, Jochen,Petry, Stefan
, p. 125 - 139 (2007/10/02)
The spacer-modified disaccharide 1,10-di-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-azi-1,10-decanediol (10) that mimics the biantennary core heptasaccharide of N-glycoproteins has been synthesised.Compound 10 is an excellent acceptor in galactosyltransferase-catalysed galactosylation by UDP-galactose, is superior (7-8 fold) to analogues that have only one GlcNAc unit, and is an efficient photoaffinity reagent for galactosyltransferase.In the presence of UDP-Gal, no photoaffinity labelling by 10 takes place, which agrees with the mechanism of galactosyltransferase action.
