150349-65-8Relevant articles and documents
Guided rational design with scaffold hopping leading to novel histamine H3 receptor ligands
Ghamari, Nakisa,Kouhi Hargelan, Saeed,Zivkovic, Aleksandra,Leitzbach, Luisa,Dastmalchi, Siavoush,Stark, Holger,Hamzeh-Mivehroud, Maryam
, (2021/10/16)
During the past decades, histamine H3 receptors have received widespread attention in pharmaceutical research due to their involvement in pathophysiology of several diseases such as neurodegenerative disorders. In this context, blocking of thes
NEW PHENYLSULFAMOYL BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS
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Page/Page column 26-27, (2008/12/05)
The present invention relates to new sulfonamide derivatives of formula (I), wherein R1-R8 and Z are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for producing these same compounds, pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.
[4-(Benzo[B]Thiophen-2-Yl) Pyrimidin-2-Yl]-Amine Derivatives As Ikk-Beta Inhibitors For The Treatment Of Cancer And Inflammatory Diseases
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Page/Page column 6, (2009/01/20)
The present invention provides compounds of Formula I: useful in the treatment of cancer and inflammatory diseases.