151898-33-8

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• Basic information

  1. Product Name: 6-Chloro-N-((hexahydro-1H-pyrrolizin-1-yl)methyl)imidazo(1,2-a)pyridin e-8-carboxamide (1S-cis)-
  2. Synonyms: 6-Chloro-N-((hexahydro-1H-pyrrolizin-1-yl)methyl)imidazo(1,2-a)pyridin e-8-carboxamide (1S-cis)-;SC 53606
  3. CAS NO:151898-33-8
  4. Molecular Formula: C16H19 Cl N4 O
  5. Molecular Weight: 318.8
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 151898-33-8.mol
  9. Article Data: 2

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: °Cat760mmHg
  3. Flash Point: °C
  4. Appearance: /
  5. Density: 1.49g/cm³
  6. Refractive Index: 1.732
  7. Storage Temp.: N/A
  8. Solubility: N/A
  9. CAS DataBase Reference: 6-Chloro-N-((hexahydro-1H-pyrrolizin-1-yl)methyl)imidazo(1,2-a)pyridin e-8-carboxamide (1S-cis)-(CAS DataBase Reference)
  10. NIST Chemistry Reference: 6-Chloro-N-((hexahydro-1H-pyrrolizin-1-yl)methyl)imidazo(1,2-a)pyridin e-8-carboxamide (1S-cis)-(151898-33-8)
  11. EPA Substance Registry System: 6-Chloro-N-((hexahydro-1H-pyrrolizin-1-yl)methyl)imidazo(1,2-a)pyridin e-8-carboxamide (1S-cis)-(151898-33-8)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 151898-33-8(Hazardous Substances Data)

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151898-33-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 151898-33-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,8,9 and 8 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 151898-33:
(8*1)+(7*5)+(6*1)+(5*8)+(4*9)+(3*8)+(2*3)+(1*3)=158
158 % 10 = 8
So 151898-33-8 is a valid CAS Registry Number.

InChI:InChI=1/C16H19ClN4O/c17-12-8-13(15-18-4-7-21(15)10-12)16(22)19-9-11-3-6-20-5-1-2-14(11)20/h4,7-8,10-11,14H,1-3,5-6,9H2,(H,19,22)/t11-,14-/m0/s1

151898-33-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	6-chloro-N-[[(1S,8S)-2,3,5,6,7,8-hexahydro-1H-pyrrolizin-1-yl]methyl]imidazo[1,2-a]pyridine-8-carboxamide

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:151898-33-8 SDS

151898-33-8Upstream product

• 107-20-0 2-chloroethanal 
• 526-64-7 laburnine 
• 50735-33-6 methyl 2-amino-5-chloro-3-pyridinecarboxylate 
• 14667-47-1 methyl 2-aminonicotinate 
• 5345-47-1 2-aminopyridin-3-carboxylic acid 
• 141119-76-8 2-[(1S,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl]-1H-isoindole-1,3(2H)-dione 
• 760144-55-6 methyl 6-chloroimidazol[1,2-a]pyridine-8-carboxylate 
• 141197-04-8 (1S,7aS)-hexahydro-1H-pyrrolizin-1-ylmethylamine 
• 111975-23-6 (S)-5-[(R)-3-Chloro-1-((S)-4-isopropyl-2-thioxo-thiazolidine-3-carbonyl)-propyl]-pyrrolidin-2-one 

151898-33-8Downstream Products

151898-33-8Relevant articles and documents

Synthesis method and applications of polysubstituted 2-aminopyridine derivative

-

Paragraph 0081; 0082; 0084, (2020/04/22)

The invention belongs to the field of organic synthetic chemistry, and relates to a synthetic method and applications of a polysubstituted 2-aminopyridine derivative. According to the method, a 1,2,3-triazine compound and a cyanomethyl compound are used as substrates and are subjected to a one-step cycloaddition reaction under an alkaline condition to obtain a polysubstituted 2-aminopyridine derivative, wherein the reaction does not involve in danger and control reagents and medicines, and a simple, safe, efficient and environment-friendly strategy is provided for synthesizing the polysubstituted 2-aminopyridine derivative. According to the present invention, the obtained product is subjected to further derivatization, such that the active molecule or the drug molecule containing the 2-aminopyridine structure can be synthesized, such as active molecule SC-53606, drug molecule apatinib and nevirapine.

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