1527-17-9 Usage
Description
2-[2-(Phenylthio)phenyl]acetic acid is an organic compound characterized by a unique molecular structure that includes an acetic acid group, a phenylthio group, and two phenyl rings. 2-[2-(PHENYLTHIO)PHENYL]ACETIC ACID's aromatic nature, conferred by the phenyl rings, suggests stability and strong intermolecular forces. As an acid, it has the capacity to donate a proton (H+) in chemical reactions. The phenylthio group, which consists of a sulfur atom connected to a phenyl ring and a hydrogen atom, may introduce potential bioactivity or instability, given the known reactivity of sulfur-containing compounds. The specific behavior, reactivity, and applications of this compound are influenced by the precise positioning of these functional groups and the overall molecular geometry.
Uses
Used in Pharmaceutical Industry:
2-[2-(Phenylthio)phenyl]acetic acid is used as a potential pharmaceutical compound for its possible bioactivity, which could be harnessed for the development of new drugs. The presence of the phenylthio group may contribute to its interaction with biological targets, making it a candidate for further exploration in drug discovery.
Used in Chemical Research:
In the field of chemical research, 2-[2-(Phenylthio)phenyl]acetic acid serves as a subject for studying the effects of molecular structure on chemical reactivity and stability. Its phenylthio group and aromatic rings provide a basis for investigating the influence of these functional groups on the compound's properties and potential applications.
Used in Material Science:
2-[2-(Phenylthio)phenyl]acetic acid may be utilized in material science as a component in the synthesis of new materials with specific properties. 2-[2-(PHENYLTHIO)PHENYL]ACETIC ACID's aromaticity and the presence of the phenylthio group could contribute to the development of materials with tailored characteristics for various applications, such as in electronics or as specialty coatings.
Check Digit Verification of cas no
The CAS Registry Mumber 1527-17-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,2 and 7 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1527-17:
(6*1)+(5*5)+(4*2)+(3*7)+(2*1)+(1*7)=69
69 % 10 = 9
So 1527-17-9 is a valid CAS Registry Number.
InChI:InChI=1/C14H12O2S/c15-14(16)10-11-6-4-5-9-13(11)17-12-7-2-1-3-8-12/h1-9H,10H2,(H,15,16)
1527-17-9Relevant articles and documents
Redox-Neutral α-Arylation of Alkyl Nitriles with Aryl Sulfoxides: A Rapid Electrophilic Rearrangement
Shang, Li,Chang, Yonghui,Luo, Fan,He, Jia-Ni,Huang, Xin,Zhang, Lei,Kong, Lichun,Li, Kaixiao,Peng, Bo
supporting information, p. 4211 - 4217 (2017/03/27)
A facile α-arylation of nitriles has been developed by simply introducing Tf2O and DABCO to the mixture of nitriles and aryl sulfoxides. The transformation consists of two sequential steps: (i) Tf2O-initiated electrophilic assembly a
Overcoming chloroquine resistance in malaria: Design, synthesis and structure-activity relationships of novel chemoreversal agents
Boudhar, Aicha,Ng, Xiao Wei,Loh, Chiew Yee,Chia, Wan Ni,Tan, Zhi Ming,Nosten, Francois,Dymock, Brian W.,Tan, Kevin S.W.
, p. 231 - 249 (2016/05/24)
Malaria remains a significant infectious disease with even artemisinin-based therapies now facing resistance in the field. Development of new therapies is urgently needed, either by finding new compounds with unique modes of action, or by reversing resistance towards known drugs with 'chemosensitizers' or 'chemoreversal' agents (CRA). Concerning the latter, we have focused on the resistance mechanisms developed against chloroquine (CQ). We have synthesized a series of compounds related to previously identified CRAs, and found promising novel compounds. These compounds show encouraging results in a coumarin labeled chloroquine uptake assay, exhibiting a dose response in resensitising parasites to the antimalarial effects of chloroquine. Selected compounds show consistent potency across a panel of chloroquine and artemisinin sensitive and resistant parasites, and a wide therapeutic window. This data supports further study of CRAs in the treatment of malaria and, ultimately, their use in chloroquine-based combination therapies.
SPIRO COMPOUNDS USEFUL AS ANTAGONISTS OF THE H1 RECEPTOR
-
Page/Page column 37, (2009/03/07)
The invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, for treating diseases and conditions of the central nervous system (CNS), in particular sleep disorders.
