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15965-54-5

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15965-54-5 Usage

General Description

2-Chloro-5-methoxybenzimidazole, also known by the chemical formula C8H7ClN2O, is a heterocyclic compound with a chloro substituent at position 2 and a methoxy group at position 5 of the benzimidazole ring. It is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. The compound has shown potential antibacterial and antifungal properties, and research has also suggested its potential use in the treatment of various diseases. 2-Chloro-5-methoxybenzimidazole is considered an important intermediate in organic synthesis and finds applications in the production of a wide range of pharmaceutical and agricultural products.

Check Digit Verification of cas no

The CAS Registry Mumber 15965-54-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,9,6 and 5 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 15965-54:
(7*1)+(6*5)+(5*9)+(4*6)+(3*5)+(2*5)+(1*4)=135
135 % 10 = 5
So 15965-54-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H7ClN2O/c1-12-5-2-3-6-7(4-5)11-8(9)10-6/h2-4H,1H3,(H,10,11)

15965-54-5 Well-known Company Product Price

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  • Alfa Aesar

  • (L08440)  2-Chloro-5-methoxybenzimidazole, 94%   

  • 15965-54-5

  • 250mg

  • 730.0CNY

  • Detail
  • Alfa Aesar

  • (L08440)  2-Chloro-5-methoxybenzimidazole, 94%   

  • 15965-54-5

  • 1g

  • 2269.0CNY

  • Detail

15965-54-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Chloro-5-Methoxybenzimidazole

1.2 Other means of identification

Product number -
Other names 2-Chloro-5-methoxy-1H-benzo[d]imidazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15965-54-5 SDS

15965-54-5Relevant articles and documents

Method for preparing benzimidazole compound

-

Paragraph 0025-0026, (2018/03/24)

The invention discloses a method for preparing a benzimidazole compound, namely 5-methoxyl-2-(4-methylpiperidine-1-yl)-1H-benzo[d]imidazole. The method comprises the following steps of using 5-methoxyl-2-nitroaniline as the initiating raw material, and performing reduction, loop closing, chloridizing and nucleophilic reaction, so as to obtain a target product. The compound is an important medicineintermediate.

4-(2-Pyridyl)piperazine-1-benzimidazoles as potent TRPV1 antagonists

Shao, Bin,Huang, Jincheng,Sun, Qun,Valenzano, Kenneth J.,Schmid, Lori,Nolan, Scott

, p. 719 - 723 (2007/10/03)

A series of 4-(2-pyridyl)piperazine-1-benzimidazole analogues based on compound 1 was synthesized and evaluated for TRPV1 antagonist activity in capsaicin-induced (CAP) and pH 5.5-induced (pH) FLIPR assays in a human TRPV1-expressing HEK293 cell line. Potent TRPV1 antagonists were identified through SAR studies. From these studies, several antagonists were found, with IC50 values ranging from 32 nM to ~5000 nM. Among these, 11 [IC50 = 90 nM (CAP) and 104 nM (pH)] was further evaluated and found to be orally available in rats (F% = 19.7).

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