159996-18-6Relevant articles and documents
Serotonin 5-HT4, agonist activity of a series of meso-azanoradamantane benzamides
Becker, Daniel P.,Nosal, Roger,Villamil, Clara I.,Gullikson, Gary,Moummi, Chafiq,Yang, Dai-Chang,Flynn, Daniel L.
, p. 2149 - 2154 (2007/10/03)
A series of meso-amino(methyl)azanoradamantane benzamides has been prepared and evaluated for 5-HT4, agonism activity in the rat tunica muscularis mucosae (TMM) assay. Compound 8i is the most potent 5-HT4, agonist in the series, with an EC50 of 217 nM.