159996-17-5Relevant academic research and scientific papers
Serotonin 5-HT4, agonist activity of a series of meso-azanoradamantane benzamides
Becker, Daniel P.,Nosal, Roger,Villamil, Clara I.,Gullikson, Gary,Moummi, Chafiq,Yang, Dai-Chang,Flynn, Daniel L.
, p. 2149 - 2154 (1997)
A series of meso-amino(methyl)azanoradamantane benzamides has been prepared and evaluated for 5-HT4, agonism activity in the rat tunica muscularis mucosae (TMM) assay. Compound 8i is the most potent 5-HT4, agonist in the series, with an EC50 of 217 nM.
MESO-AZANORADAMANTANES
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, (2008/06/13)
This invention relates to compounds of the formula: STR1 or a pharmaceutically acceptable salt thereof wherein Z is selected from the group consisting of STR2 R 1 is alkoxy of one to six carbon atoms; R. sub.2, R 3, R 4 and R 5 are the same or different a
