16256-42-1Relevant articles and documents
Novel N-chloroheterocyclic antimicrobials
Francavilla, Charles,Turtle, Eric D.,Kim, Bum,O'Mahony, Donogh J.R.,Shiau, Timothy P.,Low, Eddy,Alvarez, Nichole J.,Celeri, Chris E.,D'Lima, Louisa,Friedman, Lisa C.,Ruado, Francis S.,Xu, Ping,Zuck, Meghan E.,Anderson, Mark B.,Najafi, Ramin,Jain, Rakesh K.
scheme or table, p. 3029 - 3033 (2011/06/24)
Antimicrobial compounds with broad-spectrum activity and minimal potential for antibiotic resistance are urgently needed. Toward this end, we prepared and investigated a novel series of N-chloroheterocycles. Of the compounds examined, the N-chloroamine series were found superior over N-chloroamide series in regards to exhibiting high antimicrobial activity, low cytotoxicity, and long-term aqueous stability.
Imidazolidinone derivatives
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, (2008/06/13)
A compound of the formula (IA) or (IB) wherein G1, G2, G3 and G4 are independently of one another C1-C18alkyl or C5-C12cycloalkyl or the radicals G1 and G2 and the radicals G3 and G4 form independently of one another, together with the carbon atom they are attached to, C5-C12cycloalkyl; R is hydrogen C1-C18alkyl, C1-C18hydroxyalkyl, C2-C18alkenyl, C5-C12cycloalkyl, C7-C12phenylalkyl unsubstituted or substituted on the phenyl radical by C1-C4alkyl and/or C1-C4alkoxy; or C1-C18alkanoyl; R* is hydrogen, C1-C18alkyl, oxyl, —OH, —CH2CN, C3-C6alkenyl, C3-C8alkynyl, C7-C12phenylalkyl unsubstituted or substituted on the phenyl radical by C1-C4alkyl and/or C1-C4alkoxy; C1-C8acyl, C1-C18alkoxy, C1-C18hydroxyalkoxy, C2-C18alkenyloxy, C5-C12cycloalkoxy, C7-C12phenylalkoxy unsubstituted or substituted on the phenyl radical by C1-C4alkyl and/or C1-C4alkoxy; C1-C18alkanoyloxy, (C1-C18alkoxy)carbonyl, glycidyl or a group —CH2CH(OH)(G) with G being hydrogen, methyl or phenyl; n is 1, 2, 3 or 4; n* is 1, 2 or 3; X is an organic radical of a valency equal to n; and X* is a triazinic radical with a valency equal to n*; with the proviso that when n is 1, R is methyl, ethyl, propyl, C1-C18hydroxyalkyl, C2-C18alkenyl, C5-C12cycloalkyl or C1-C18alkanoyl. The compounds described above are useful for stabilizing an organic material against degradation induced by light, heat or oxidation.
