16544-67-5 Usage
General Description
6-(Trifluoromethyl)quinazolin-4(3H)-one is a chemical compound with the molecular formula C9H5F3N2O. It is a quinazolinone derivative, which is a class of compounds with a variety of biological and pharmacological activities. 6-(TRIFLUOROMETHYL)QUINAZOLIN-4(3H)-ONE is characterized by the presence of a trifluoromethyl group, which can enhance the lipophilicity and metabolic stability of the molecule, making it a potential candidate for drug development. Quinazolinone derivatives have been studied for their potential as anticancer, antifungal, and antiviral agents, as well as for their activity on the central nervous system. The unique structure and properties of 6-(trifluoromethyl)quinazolin-4(3H)-one make it a promising target for further research in the field of medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 16544-67-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,5,4 and 4 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 16544-67:
(7*1)+(6*6)+(5*5)+(4*4)+(3*4)+(2*6)+(1*7)=115
115 % 10 = 5
So 16544-67-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H5F3N2O/c10-9(11,12)5-1-2-7-6(3-5)8(15)14-4-13-7/h1-4H,(H,13,14,15)
16544-67-5Relevant articles and documents
Visible-Light Photosynthesis of CHF2/CClF2/CBrF2-Substituted Ring-fused Quinazolinones in Dimethyl Carbonate
Gui, Qing-Wen,He, Wei-Min,Huang, Wen-Jie,Lu, Zi-Qin,Ouyang, Wen-Tao,Teng, Fan,Xun, Changping,Yang, Hao,Zhu, Meng-Xue
, (2021/12/01)
With eco-friendly and sustainable CO2-derived dimethyl carbonate as the sole solvent, the visible-light-induced cascade radical reactions have been established as a green and efficient tool for constructing various CHF2/CClF2/CBrF2-substituted ring-fused quinazolinones.
Quinazolinone and isoquinolinone derivative
-
Paragraph 0442; 0443, (2016/10/08)
The present invention relates to quinazolinone and isoquinolinone derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
Cyclic derivatives as modulators of chemokine receptor activity
-
Page/Page column 41, (2008/06/13)
The present application describes modulators of MCP-1 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the treatment of rheumatoid arthritis, multiple sclerosis, atherosclerosis and asthma.
