1673-99-0 Usage
General Description
Ibogamine is a psychoactive indole alkaloid derived from the root bark of the Tabernanthe iboga plant. It has a unique chemical structure, with a tetracyclic core and a variety of functional groups. Ibogamine has been studied for its potential therapeutic effects on addiction and depression, as well as its hallucinogenic properties. It is known to interact with various neurotransmitter systems in the brain, including serotonin, dopamine, and glutamate, and may modulate the activity of these systems to produce its psychoactive effects. As a result, it has been of interest for its potential use in treating substance abuse disorders and mental health conditions. However, its psychoactive effects and potential for toxicity also raise concerns about its safety and regulation. Ibogamine is a complex and intriguing chemical compound with diverse potential applications and risks.
Check Digit Verification of cas no
The CAS Registry Mumber 1673-99-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,7 and 3 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1673-99:
(6*1)+(5*6)+(4*7)+(3*3)+(2*9)+(1*9)=100
100 % 10 = 0
So 1673-99-0 is a valid CAS Registry Number.
1673-99-0Relevant articles and documents
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Bellefon et al.
, p. 1649 (1975)
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Kupchan et al.
, p. 1251 (1966)
Reductive Heck coupling: An efficient approach toward the iboga alkaloids. Synthesis of ibogamine, epiibogamine and iboga analogs
Jana, Goutam Kumar,Sinha, Surajit
, p. 1671 - 1674 (2012/04/11)
A mild and efficient synthetic route to the iboga scaffold by employing reductive-Heck type annulation is described. The utility of this process is demonstrated by the direct access to the ibogamine, epiibogamine and iboga-analogs. The cyclization precursors were readily obtained from 2-iodoaniline by heteroannulation reaction with suitable alkynes followed by iodination.
A common intermediate providing syntheses of ψ-tabersonine, coronaridine, iboxyphylline, ibophyllidine, vinamidine, and vinblastine
Bornmann,Kuehne
, p. 1752 - 1760 (2007/10/02)
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1,6-Dihydro-3(2H)-pyridinones as synthetic intermediates. A novel total synthesis of (±)-ibogamine and (±)-epiibogamine
Imanishi,Yagi,Shin,Hanaoka
, p. 4001 - 4004 (2007/10/02)
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