169124-35-0Relevant articles and documents
A highly selective colorimetric chemosensor for cobalt(ii) ions based on a tripodal amide ligand
Zhou, Jing-Ru,Liu, Da-Peng,He, Yue,Kong, Xiang-Jian,Zhang, Zhi-Ming,Ren, Yan-Ping,Long, La-Sheng,Huang, Rong-Bin,Zheng, Lan-Sun
, p. 11579 - 11586 (2014)
A tripodal amide based ligand, tris-{(2-carbamoyl-5-carbomethoxy-pyridine)- 2-ethyl}amine (H3L, 1), was synthesized and structurally characterized by single crystal X-ray diffraction. Investigation of the cation recognition behavior showed that the ligand has selective colorimetric sensing properties for cobalt(ii) ions by an obvious color change from colorless to yellow. To investigate the sensing mechanism of H3L for Co 2+ ions, UV-vis absorption spectroscopy and single-crystal structural analysis were performed. The mixture of the ligand and cobalt(ii) ions displayed selective colorimetric sensing properties for weak acid anions, such as CO32-, Ac-, HCO3-, SO32-, and PO43-. Detailed 1H NMR experiments revealed that the basicity of the anions played an important role in the intensity of the interaction between the ligand and anions. The structures of compounds CoL (2), Co-Ac-HL (3), H4L- NO3 (4), and H4L-ClO4 (5) were also determined by single crystal diffraction studies. This journal is the Partner Organisations 2014.
Rh-Catalyzed Annulative Insertion of Terminal Olefin onto Pyridines via a C-H Activation Strategy Using Ethenesulfonyl Fluoride as Ethylene Provider
Li, Chen,Qin, Hua-Li
, p. 4495 - 4499 (2019/06/27)
A Rh(III)-catalyzed annulative insertion of ethylene onto picolinamides was achieved, providing a portal to a class of unique pyridine-containing molecules bearing a terminal olefin moiety for diversification. Application of this method for modification of Sorafenib was also accomplished.
ARYL HYDROCARBON RECEPTOR MODULATORS AND USES THEREOF
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Paragraph 00455, (2019/10/29)
Provided are compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, stereoisomers, tautomers, isotopically labeled derivatives, polymorphs, and prodrugs thereof, wherein X1-X4, RX, RC, RB, n, and Ring A are as defined herein. The compounds may be aryl hydrocarbon receptor agonists or partial aryl hydrocarbon receptor agonists. Also provided are pharmaceutical compositions comprising a compound of Formula (I) and methods of using such compounds for treating diseases and conditions related to the activity of an aryl hydrocarbon receptor, such as, for example, inflammatory diseases, autoimmune diseases, metabolic disorders, and proliferative diseases.