17261-12-0Relevant articles and documents
Reusable and Magnetic Palladium and Copper Oxide Catalysts in Direct ortho and meta Arylation of Anilide Derivatives
Vásquez-Céspedes, Suhelen,Holtkamp, Michael,Karst, Uwe,Glorius, Frank
supporting information, p. 2759 - 2764 (2017/12/14)
We report a general, direct C-H arylation of anilide derivatives using reusable palladium or copper oxide on magnetite as heterogeneous precatalysts. Highly selective ortho and meta arylations are achieved using electronically and sterically diverse diaryliodonium salts. Catalytically active soluble species from the heterogeneous precursors were detected by experimental techniques. Preliminary mechanistic investigation suggests different reaction pathways for each of the catalysts.
One pot synthesis of phenanthridines using a palladium-catalyzed cyclization of aromatic ketoximes with aryl iodides: Via Beckmann rearrangement
Raju, Gajula,Guguloth, Vijayacharan,Satyanarayana, Battu
, p. 45036 - 45040 (2016/06/06)
The catalytic reaction of ketoximes with aryl iodides via a Beckmann rearrangement in the presence of a catalytic amount of Pd(OAc)2, Ag2O and ZnBr2 gave substituted phenanthridines in good to excellent yield. In the reaction, aromatic ketoximes converted first to acetanilides in the presence of ZnBr2/TFA via a Beckmann rearrangement followed by arylation in the presence of palladium complex. Furthermore, ortho-arylated acetanilides were converted to phenanthridine derivatives in the presence of a Hendrickson reagent.
Rhodium(III)-catalyzed ortho-arylation of anilides with aryl halides
Haridharan, Radhakrishnan,Muralirajan, Krishnamoorthy,Cheng, Chien-Hong
supporting information, p. 366 - 370 (2015/03/05)
An efficient o-arylation of pivalamides by aryl iodides via rhodium(III)-catalyzed C-H activation is demonstrated for the first time. Further, the biaryl products can be converted effectively into biologically active phenanthridine and phenanthridinone derivative.
