72846-70-9

Basic information

• Product Name: 1-Propanone, 2-methyl-1-phenyl-, oxime, (E)-
• CAS NO: 72846-70-9
• Molecular Formula: C10H13NO
• Molecular Weight: 163.219
• Mol File: 72846-70-9.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: 1-Propanone, 2-methyl-1-phenyl-, oxime, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 2-methyl-1-phenyl-, oxime, (E)-(72846-70-9)
• EPA Substance Registry System: 1-Propanone, 2-methyl-1-phenyl-, oxime, (E)-(72846-70-9)

Safety Data

• Hazardous Substances Data: 72846-70-9(Hazardous Substances Data)

Upstream product

• 611-70-1 phenyl isopropyl ketone 
• 1313533-65-1 2-methyl-1-phenylpropan-1-one O-acetyl oxime 
• 501-65-5 diphenyl acetylene 

Downstream Products

• 6668-27-5 2-methyl-1-phenyl-propylamine 
• 15545-80-9 1,1,3,3-tetraphenyldisiloxane 
• 63045-63-6 3-ethyl-2-phenyl-pyrrole 
• 58042-94-7 3-ethyl-2-phenyl-1-vinylpyrrole 
• 103660-70-4 3,3-dimethyl-2-phenyl-3H-pyrrole 
• 142266-94-2 2-methyl-1-phenyl-1-propanone O-vinyloxime 
• 92-52-4 biphenyl 
• 611-70-1 phenyl isopropyl ketone 
• 1257846-45-9 1-iso-propyl-3,4-diphenylisoquinoline 
• 1257846-47-1 1-isopropyl-4-methyl-3-phenylisoquinoline 
• 1313534-17-6 1-isopropyl-3,4-bis(4-methoxyphenyl)isoquinoline 
• 1313534-19-8 3,4-bis(4-bromophenyl)-1-isopropylisoquinoline 
• 1313534-24-5 4-((tert-butyldimethylsilyloxy)methyl)-1-isopropyl-3-phenylisoquinoline 
• 1313534-31-4 C₂₅H₃₃NOSi 

Relevant articles and documents

Photocatalyzed Triplet Sensitization of Oximes Using Visible Light Provides a Route to Nonclassical Beckmann Rearrangement Products

Oximes are valuable synthetic intermediates for the preparation of a variety of functional groups. To date, the stereoselective synthesis of oximes remains a major challenge, as most current synthetic methods either provide mixtures of E and Z isomers or furnish the thermodynamically preferred E isomer. Herein we report a mild and general method to achieve Z isomers of aryl oximes by photoisomerization of oximes via visible-light-mediated energy transfer (EnT) catalysis. Facile access to (Z)-oximes provides opportunities to achieve regio- and chemoselectivity complementary to those of widely used transformations employing oxime starting materials. We show an enhanced one-pot protocol for photocatalyzed oxime isomerization and subsequent Beckmann rearrangement that enables novel reactivity with alkyl groups migrating preferentially over aryl groups, reversing the regioselectivity of the traditional Beckmann reaction. Chemodivergent N- or O- cyclizations of alkenyl oximes are also demonstrated, leading to nitrones or cyclic oxime ethers, respectively.

Copper-catalyzed synthesis of oxime ethers from iminoxy radical (C[dbnd]N–O[rad]) and maleimides via radical addition

An efficient Cu(II)-catalyzed radical addition of maleimides has been achieved. The identified copper catalyst enables the formation of oxime radicals (N–O[rad]) by cleaving the O–H bond in ketoximes, followed by the radical addition to N-substituted male

Copper-Catalyzed Unstrained C-C Single Bond Cleavage of Acyclic Oxime Acetates Using Air: An Internal Oxidant-Triggered Strategy toward Nitriles and Ketones

A copper-catalyzed aerobic oxidative C-C single bond cleavage of acyclic unstrained oxime acetates is reported, providing various aryl nitriles and ketones in good yields. Mechanistic studies indicate a radical procedure is involved in this transformation, and the oxygen atom in the ketone products is originated from O2 in the air. Oxime acetates as an internal oxidant have been proved to be an initiator, which may promote the discovery of novel protocol for C-C bond cleavage and dioxygen activation.