178040-94-3Relevant articles and documents
Visible-light-accelerated amination of quinoxalin-2-ones and benzo[1,4]oxazin-2-ones with dialkyl azodicarboxylates under metal and photocatalyst-free conditions
Blay, Gonzalo,Capella-Argente, Murta,Pedro, José R.,Rostoll-Berenguer, Jaume,Vila, Carlos
, p. 6250 - 6255 (2021/07/28)
A direct sp3C-H amination of cyclic amines (dihydroquinoxalinones and dihydrobenzoxazinones) with dialkyl azo dicarboxylates accelerated by visible-light irradiation under metal and photocatalyst-free conditions is described. This protocol features very mild reaction conditions for the synthesis of aminal quinoxaline and benzoxazine derivatives with good to high yields (up to 99%). These aminal derivatives respresent versatile building blocks for the divergent synthesis of quinoxalin-2-one derivatives.
Highly efficient synthesis of quinoxalinone-N-oxide via tandem nitrosation/aerobic oxidative C-N bond formation
Kobayashi, Yusuke,Kuroda, Mami,Toba, Natsuki,Okada, Mari,Tanaka, Rie,Kimachi, Tetsutaro
, p. 6280 - 6283 (2012/01/06)
An efficient method for constructing quinoxalinone-N-oxides from cyanoacetanilides has been developed. This transformation can be achieved using inexpensive reagents and molecular oxygen under mild conditions, thus offering a practical pathway to quinoxalinone-containing pharmaceuticals such as ataquimast and opaviraline.
